Topic description and stories

New technologies and strong academic-industry partnerships have the potential to change the face of therapeutic medicine.

Cambridge Enterprise joins largest early stage investment in a university spin-out

04 Oct 2016

Cambridge spin-out Carrick Therapeutics raises $95 million in funding, representing the largest-ever early stage investment in a UK university spin-...

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Dementia: Catching the memory thief

21 Sep 2016

It's over a hundred years since the first case of Alzheimer鈥檚 disease was diagnosed. Since then we鈥檝e learned a great deal about the protein 鈥榯angles...

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Parkinson鈥檚 Disease protein plays vital 鈥渕arshalling鈥 role in healthy brains

19 Sep 2016

Researchers have identified how alpha-synuclein, the protein associated with Parkinson鈥檚 Disease, enables communication between neurons in the brain...

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Crystal structure of parallel quadruplexes from human telomeric DNA.

Quadruple helix form of DNA may aid in the development of targeted cancer therapies

12 Sep 2016

Researchers have identified the role that a four-stranded version of DNA may play in the role of cancer progression, and suggest that it may be used...

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Image of an oesophageal carcinoma

Oesophageal cancer treatments could be tailor-made for individual patients, study finds

06 Sep 2016

Tailored, targeted treatment for patients with oesophageal cancer could be developed after scientists discovered that the disease can be classified...

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Artificial pancreas trial in young children with diabetes receives 鈧4.6millon grant from European Commission

05 Sep 2016

An international trial to test whether an artificial pancreas can help young children manage their type 1 diabetes will begin next year, thanks to a...

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Image of 鈥渁myloid fibrils鈥; thread-like structures which form after the protein alpha-synuclein aggregates. Plaques (protein deposits) consisting of this protein have been found in the brains of Parkinson 鈥檚 Disease patients and linked to disease.

Tiny changes in Parkinson鈥檚 protein can have 鈥渄ramatic鈥 impact on processes that lead to the disease

30 Aug 2016

Specific mutations in the protein associated with Parkinson鈥檚 Disease, in which just one of its 140 building blocks is altered, can make a dramatic...

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In healthy tissues, a gene expression signature associated with amyloid-beta and tau aggregation echoes the progression of AD well before the onset of the disease.

Gene signature in healthy brains pinpoints the origins of Alzheimer鈥檚 disease

10 Aug 2016

A specific gene expression pattern maps out which parts of the brain are most vulnerable to Alzheimer鈥檚 disease, decades before symptoms appear, and...

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FAMIN or feast? Newly-discovered mechanism influences how immune cells 鈥榚at鈥 invading bacteria

01 Aug 2016

A new mechanism that affects how our immune cells perform 鈥 and hence their ability to prevent disease 鈥 has been discovered by an international team...

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Artist鈥檚 rendering of protein fibrils (in blue) and healthy proteins from computer simulations

Slow, slow, quick quick, slow: Scientists discover how proteins in the brain build up rapidly in Alzheimer鈥檚 disease

18 Jul 2016

Cambridge researchers have identified 鈥 and shown that it may be possible to control 鈥 the mechanism that leads to the rapid build-up of the disease-...

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Claire Pesterfield and Magic

Diabetes sniffer dogs? 鈥楽cent鈥 of hypos could aid development of new tests

27 Jun 2016

A chemical found in our breath could provide a flag to warn of dangerously-low blood sugar levels in patients with type 1 diabetes, according to new...

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Diabetes

Genetic approach could help identify side-effects at early stages of drug development

01 Jun 2016

An approach that could reduce the chances of drugs failing during the later stages of clinical trials has been demonstrated by a collaboration...

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