Topic description and stories

DNA

Researchers call for greater awareness of unintended consequences of CRISPR gene editing

12 Apr 2021

CRISPR-Cas9 genome editing can lead to unintended mutations at the targeted section of DNA in early human embryos, researchers have revealed. This...

Read more
Alexis Braun

Women in STEM: Dr Alexis Braun

26 Sep 2019

Dr Alexis Braun is a postdoctoral researcher in the Department of Genetics. Here, she tells us about the importance of mentors, how her research...

Read more
Scissors cut metal

Genome-editing tool could increase cancer risk in cells, say researchers

11 Jun 2018

More research needs to be done to understand whether CRISPR-Cas9 – molecular ‘scissors’ that make gene editing a possibility – may inadvertently...

Read more

Genome editing reveals role of gene important for human embryo development

20 Sep 2017

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development. This is the...

Read more

Snip, snip, cure: correcting defects in the genetic blueprint

14 Jul 2017

Gene editing using ‘molecular scissors’ that snip out and replace faulty DNA could provide an almost unimaginable future for some patients: a...

Read more

Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type

29 Nov 2016

Researchers from the Wellcome Trust Sanger Institute and the ̽»¨Ö±²¥ of Cambridge have created sOPTiKO, a more efficient and enhanced inducible...

Read more