探花直播 of Cambridge - Anders Hansen /taxonomy/people/anders-hansen en Mathematical paradox demonstrates the limits of AI /research/news/mathematical-paradox-demonstrates-the-limits-of-ai <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/datawave.jpg?itok=vOvnoWrF" alt="A glowing particle and binary wave pattern on dark background." title="Binary data wave, Credit: Yuichiro Chino" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>Like some people, AI systems often have a degree of confidence that far exceeds their actual abilities. And like an overconfident person, many AI systems don鈥檛 know when they鈥檙e making mistakes. Sometimes it鈥檚 even more difficult for an AI system to realise when it鈥檚 making a mistake than to produce a correct result.</p> <p>Researchers from the 探花直播 of Cambridge and the 探花直播 of Oslo say that instability is the Achilles鈥 heel of modern AI and that a mathematical paradox shows AI鈥檚 limitations. Neural networks, the state-of-the-art tool in AI, roughly mimic the links between neurons in the brain. 探花直播researchers show that there are problems where stable and accurate neural networks exist, yet no algorithm can produce such a network. Only in specific cases can algorithms compute stable and accurate neural networks.</p> <p> 探花直播researchers propose a classification theory describing when neural networks can be trained to provide a trustworthy AI system under certain specific conditions. Their <a href="https://www.pnas.org/doi/10.1073/pnas.2107151119">results</a> are reported in the <em>Proceedings of the National Academy of Sciences</em>.</p> <p>Deep learning, the leading AI technology for pattern recognition, has been the subject of numerous breathless headlines. Examples include diagnosing disease more accurately than physicians or preventing road accidents through autonomous driving. However, many deep learning systems are untrustworthy and <a href="https://www.nature.com/articles/d41586-019-03013-5">easy to fool</a>.</p> <p>鈥淢any AI systems are unstable, and it鈥檚 becoming a major liability, especially as they are increasingly used in high-risk areas such as disease diagnosis or autonomous vehicles,鈥 said co-author Professor Anders Hansen from Cambridge鈥檚 Department of Applied Mathematics and Theoretical Physics. 鈥淚f AI systems are used in areas where they can do real harm if they go wrong, trust in those systems has got to be the top priority.鈥</p> <p> 探花直播paradox identified by the researchers traces back to two 20th century mathematical giants: Alan Turing and Kurt G枚del. At the beginning of the 20th century, mathematicians attempted to justify mathematics as the ultimate consistent language of science. However, Turing and G枚del showed a paradox at the heart of mathematics: it is impossible to prove whether certain mathematical statements are true or false, and some computational problems cannot be tackled with algorithms. And, whenever a mathematical system is rich enough to describe the arithmetic we learn at school, it cannot prove its own consistency.</p> <p>Decades later, the mathematician Steve Smale proposed a list of 18 unsolved mathematical problems for the 21st century. 探花直播18th problem concerned the limits of intelligence for both humans and machines.</p> <p>鈥 探花直播paradox first identified by Turing and G枚del has now been brought forward into the world of AI by Smale and others,鈥 said co-author Dr Matthew Colbrook from the Department of Applied Mathematics and Theoretical Physics. 鈥淭here are fundamental limits inherent in mathematics and, similarly, AI algorithms can鈥檛 exist for certain problems.鈥</p> <p> 探花直播researchers say that, because of this paradox, there are cases where good neural networks can exist, yet an inherently trustworthy one cannot be built. 鈥淣o matter how accurate your data is, you can never get the perfect information to build the required neural network,鈥 said co-author Dr Vegard Antun from the 探花直播 of Oslo.</p> <p> 探花直播impossibility of computing the good existing neural network is also true regardless of the amount of training data. No matter how much data an algorithm can access, it will not produce the desired network. 鈥淭his is similar to Turing鈥檚 argument: there are computational problems that cannot be solved regardless of computing power and runtime,鈥 said Hansen.</p> <p> 探花直播researchers say that not all AI is inherently flawed, but it鈥檚 only reliable in specific areas, using specific methods. 鈥 探花直播issue is with areas where you need a guarantee, because many AI systems are a black box,鈥 said Colbrook. 鈥淚t鈥檚 completely fine in some situations for an AI to make mistakes, but it needs to be honest about it. And that鈥檚 not what we鈥檙e seeing for many systems 鈥 there鈥檚 no way of knowing when they鈥檙e more confident or less confident about a decision.鈥</p> <p>鈥淐urrently, AI systems can sometimes have a touch of guesswork to them,鈥 said Hansen.鈥淵ou try something, and if it doesn鈥檛 work, you add more stuff, hoping it works. At some point, you鈥檒l get tired of not getting what you want, and you鈥檒l try a different method. It鈥檚 important to understand the limitations of different approaches. We are at the stage where the practical successes of AI are far ahead of theory and understanding. A program on understanding the foundations of AI computing is needed to bridge this gap.鈥</p> <p>鈥淲hen 20th-century mathematicians identified different paradoxes, they didn鈥檛 stop studying mathematics. They just had to find new paths, because they understood the limitations,鈥 said Colbrook. 鈥淔or AI, it may be a case of changing paths or developing new ones to build systems that can solve problems in a trustworthy and transparent way, while understanding their limitations.鈥</p> <p> 探花直播next stage for the researchers is to combine approximation theory, numerical analysis and foundations of computations to determine which neural networks can be computed by algorithms, and which can be made stable and trustworthy. Just as the paradoxes on the limitations of mathematics and computers identified by G枚del and Turing led to rich foundation theories 鈥 describing both the limitations and the possibilities of mathematics and computations 鈥 perhaps a similar foundations theory may blossom in AI.</p> <p>Matthew Colbrook is a Junior Research Fellow at Trinity College, Cambridge. Anders Hansen is a Fellow at Peterhouse, Cambridge. 探花直播research was supported in part by the Royal Society.</p> <p>聽</p> <p><em><strong>Reference:</strong><br /> Matthew J聽Colbrook, Vegard Antun, and Anders C聽Hansen. 鈥<a href="https://www.pnas.org/doi/10.1073/pnas.2107151119"> 探花直播difficulty of computing stable and accurate neural networks 鈥 On the barriers of deep learning and Smale鈥檚 18th problem</a>.鈥 Proceedings of the National Academy of Sciences (2022). DOI: 10.1073/pnas.2107151119</em></p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Humans are usually pretty good at recognising when they get things wrong, but artificial intelligence systems are not. According to a new study, AI generally suffers from inherent limitations due to a century-old mathematical paradox.</p> </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">There are fundamental limits inherent in mathematics and, similarly, AI algorithms can鈥檛 exist for certain problems</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Matthew Colbrook</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/" target="_blank">Yuichiro Chino</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Binary data wave</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br /> 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>. Images, including our videos, are Copyright 漏 探花直播 of Cambridge and licensors/contributors as identified.聽 All rights reserved. We make our image and video content available in a number of ways 鈥 as here, on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Thu, 17 Mar 2022 16:05:06 +0000 sc604 230711 at AI techniques in medical imaging may lead to incorrect diagnoses /research/news/ai-techniques-in-medical-imaging-may-lead-to-incorrect-diagnoses <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/markus-spiske-gcgves5hac-unsplash1.jpg?itok=J0XtwqV5" alt="" title="Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p align="LEFT" dir="LTR">A team of researchers, led by the 探花直播 of Cambridge and Simon Fraser 探花直播, designed a series of tests for medical image reconstruction algorithms based on AI and deep learning, and found that these techniques result in myriad artefacts, or unwanted alterations in the data, among other major errors in the final images. 探花直播effects were typically not present in non-AI based imaging techniques.</p>&#13; &#13; <p align="LEFT" dir="LTR"> 探花直播phenomenon was widespread across different types of artificial neural networks, suggesting that the problem will not be easily remedied. 探花直播researchers caution that relying on AI-based image reconstruction techniques to make diagnoses and determine treatment could ultimately do harm to patients. Their <a href="https://www.pnas.org/doi/10.1073/pnas.1907377117">results</a> are reported in the <em>Proceedings of the National Academy of Sciences</em>.</p>&#13; &#13; <p align="LEFT" dir="LTR">"There鈥檚 been a lot of enthusiasm about AI in medical imaging, and it may well have the potential to revolutionise modern medicine: however, there are potential pitfalls that must not be ignored," said Dr Anders Hansen from Cambridge鈥檚 Department of Applied Mathematics and Theoretical Physics, who led the research with Dr Ben Adcock from Simon Fraser 探花直播. "We鈥檝e found that AI techniques are highly unstable in medical imaging, so that small changes in the input may result in big changes in the output."</p>&#13; &#13; <p align="LEFT" dir="LTR">A typical MRI scan can take anywhere between 15 minutes and two hours, depending on the size of the area being scanned and the number of images being taken. 探花直播longer the patient spends inside the machine, the higher resolution the final image will be. However, limiting the amount of time patients spend inside the machine is desired, both to reduce the risk to individual patients and to increase the overall number of scans that can be performed.</p>&#13; &#13; <p align="LEFT" dir="LTR">Using AI techniques to improve the quality of images from MRI scans or other types of medical imaging is an attractive possibility for solving the problem of getting the highest quality image in the smallest amount of time: in theory, AI could take a low-resolution image and make it into a high-resolution version. AI algorithms 鈥榣earn鈥 to reconstruct images based on training from previous data, and through this training procedure aim to optimise the quality of the reconstruction. This represents a radical change compared to classical reconstruction techniques that are solely based on mathematical theory without dependency on previous data. In particular, classical techniques do not learn.</p>&#13; &#13; <p align="LEFT" dir="LTR">Any AI algorithm needs two things to be reliable: accuracy and stability. An AI will usually classify an image of a cat as a cat, but tiny, almost invisible changes in the image might cause the algorithm to instead classify the cat as a truck or a table, for instance. In this example of image classification, the one thing that can go wrong is that the image is incorrectly classified. However, when it comes to image reconstruction, such as that used in medical imaging, there are several things that can go wrong. For example, details like a tumour may get lost or may falsely be added. Details can be obscured and unwanted artefacts may occur in the image.</p>&#13; &#13; <p align="LEFT" dir="LTR">"When it comes to critical decisions around human health, we can鈥檛 afford to have algorithms making mistakes," said Hansen. "We found that the tiniest corruption, such as may be caused by a patient moving, can give a very different result if you鈥檙e using AI and deep learning to reconstruct medical images 鈥 meaning that these algorithms lack the stability they need."</p>&#13; &#13; <p align="LEFT" dir="LTR">Hansen and his colleagues from Norway, Portugal, Canada and the UK designed a series of tests to find the flaws in AI-based medical imaging systems, including MRI, CT and NMR. They considered three crucial issues: instabilities associated with tiny perturbations, or movements; instabilities with respect to small structural changes, such as a brain image with or without a small tumour; and instabilities with respect to changes in the number of samples.</p>&#13; &#13; <p align="LEFT" dir="LTR">They found that certain tiny movements led to myriad artefacts in the final images, details were blurred or completely removed, and that the quality of image reconstruction would deteriorate with repeated subsampling. These errors were widespread across the different types of neural networks.</p>&#13; &#13; <p align="LEFT" dir="LTR">According to the researchers, the most worrying errors are the ones that radiologists might interpret as medical issues, as opposed to those that can easily be dismissed due to a technical error.</p>&#13; &#13; <p align="LEFT" dir="LTR">"We developed the test to verify our thesis that deep learning techniques would be universally unstable in medical imaging," said Hansen. " 探花直播reasoning for our prediction was that there is a limit to how good a reconstruction can be given restricted scan time. In some sense, modern AI techniques break this barrier, and as a result become unstable. We鈥檝e shown mathematically that there is a price to pay for these instabilities, or to put it simply: there is still no such thing as a free lunch."</p>&#13; &#13; <p align="LEFT" dir="LTR"> 探花直播researchers are now focusing on providing the fundamental limits to what can be done with AI techniques. Only when these limits are known will we be able to understand which problems can be solved. "Trial and error-based research would never discover that the alchemists could not make gold: we are in a similar situation with modern AI," said Hansen. "These techniques will never discover their own limitations. Such limitations can only be shown mathematically."</p>&#13; &#13; <p align="LEFT" dir="LTR"><em><strong>Reference:</strong><br />&#13; Vegard Antun et al. 鈥<a href="https://www.pnas.org/doi/10.1073/pnas.1907377117">On instabilities of deep learning in image reconstruction and the potential costs of AI</a>.鈥 Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.1907377117</em></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Machine learning and AI are highly unstable in medical image reconstruction, and may lead to false positives and false negatives, a new study suggests.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">To put it simply: there is still no such thing as a free lunch</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Anders Hansen</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width: 0px;" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>. Images, including our videos, are Copyright 漏 探花直播 of Cambridge and licensors/contributors as identified.聽 All rights reserved. We make our image and video content available in a number of ways 鈥 as here, on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 12 May 2020 07:13:24 +0000 sc604 214502 at