探花直播 of Cambridge - empathy /taxonomy/subjects/empathy en Cambridge Festival Speaker Spotlight: Estherina Trachtenberg /stories/cambridge-festival-spotlights/estherina-trachtenberg <div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Estherina Trachtenberg is a Blavatnik Postdoctoral Fellow in the Cognition and Brain Sciences Unit, 探花直播 of Cambridge and is currently working in the lab of Prof. Duncan Astle. She studies social connectedness and its impact on health, cognition, and the underlying brain networks.</p> </p></div></div></div> Mon, 24 Feb 2025 09:26:42 +0000 zs332 248718 at Study finds that genes play a role in empathy /research/news/study-finds-that-genes-play-a-role-in-empathy <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/matheus-ferrero-159633-unsplash.jpg?itok=xb-dePe1" alt="Hand holding" title="Credit: Matheus Ferrero" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>Empathy has two parts: the ability to recognize another person鈥檚 thoughts and feelings, and the ability to respond with an appropriate emotion to someone else鈥檚 thoughts and feelings. 探花直播first part is called 鈥榗ognitive empathy鈥 and the second part 鈥榓ffective empathy鈥.</p>&#13; &#13; <p>Fifteen years ago, a team of scientists at the 探花直播 of Cambridge developed the Empathy Quotient (EQ), a brief self-report measure of empathy. 探花直播EQ measures both parts of empathy.</p>&#13; &#13; <p>Previous research showed that some of us are more empathetic than others, and that on average, women are slightly more empathetic than men. It also showed that, on average, autistic people score lower on the EQ, and that this was because they struggle with cognitive empathy, even though their affective empathy may be intact.</p>&#13; &#13; <p>In a new study published in the journal <em>Translational Psychiatry</em>, the Cambridge team, working with the genetics company 23andMe and a team of international scientists, report the results of the largest genetic study of empathy using information from more than 46,000 23andMe customers. 探花直播customers all completed the EQ online and provided a saliva sample for genetic analysis.</p>&#13; &#13; <p> 探花直播study was led by Varun Warrier, a Cambridge PhD student, and Professors Simon Baron-Cohen, Director of the Autism Research Centre at Cambridge 探花直播, Thomas Bourgeron, of the 探花直播 Paris Diderot and the Institut Pasteur, and David Hinds, Principal Scientist at 23andMe.</p>&#13; &#13; <p> 探花直播new study has three important results. First, it found that how empathetic we are is partly due to genetics. Indeed, a tenth of this variation is due to genetic factors. This confirms previous research examining empathy in identical versus non-identical twins.</p>&#13; &#13; <p>Second, the new study confirmed that women are on average more empathetic than men. However, this difference is not due to our DNA as there were no differences in the genes that contribute to empathy in men and women.</p>&#13; &#13; <p>This implies that the sex difference in empathy is the result of other non-genetic biological factors, such as prenatal hormone influences, or non-biological factors such as socialisation, both of which also differ between the sexes.</p>&#13; &#13; <p>Finally, the new study found that genetic variants associated with lower empathy are also associated with higher risk for autism.聽</p>&#13; &#13; <p>Varun Warrier said: 鈥淭his is an important step towards understanding the small but important role that genetics plays in empathy. But keep in mind that only a tenth of individual differences in empathy in the population are due to genetics. It will be equally important to understand the non-genetic factors that explain the other 90%.鈥</p>&#13; &#13; <p>Professor Thomas Bourgeron added: 鈥淭his new study demonstrates a role for genes in empathy, but we have not yet identified the specific genes that are involved. Our next step is to gather larger samples to replicate these findings, and to pin-point the precise biological pathways associated with individual differences in empathy.鈥</p>&#13; &#13; <p>Dr David Hinds said: 鈥淭hese are the latest findings from a series of studies that 23andMe have collaborated on with researchers at Cambridge. Together these are providing exciting new insights into the genetics influences underlying human behaviour.鈥</p>&#13; &#13; <p>Professor Simon Baron-Cohen added: 鈥淔inding that even a fraction of why we differ in empathy is due to genetic factors helps us understand people such as those with autism who struggle to imagine another person鈥檚 thoughts and feelings. This can give rise to disability no less challenging than other kinds of disability, such as dyslexia or visual impairment. We as a society need to support those with disabilities, with novel teaching methods, work-arounds, or reasonable adjustments, to promote inclusion.鈥</p>&#13; &#13; <p>This study also benefitted from support from the Medical Research Council, the Wellcome Trust, the Institut Pasteur, the CNRS, the 探花直播 Paris Diderot, the Bettencourt-Schueller Foundation, the Cambridge Commonwealth Trust, and St John鈥檚 College, Cambridge.</p>&#13; &#13; <p><em><strong>Reference</strong><br />&#13; <a href="https://www.nature.com/articles/s41398-017-0082-6">Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa</a>, by V Warrier, R Toro, B Chakrabarti, iPSYCH-Broad Autism Group, Grove J, Borglum AD, D Hinds, T Bourgeron, and S Baron-Cohen. Translational Psychiatry. DOI: 10.1038/s41398-017-0082-6</em></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>A new study published today suggests that how empathic we are is not just a result of our upbringing and experience but also partly a result of our genes.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">This is an important step towards understanding the small but important role that genetics plays in empathy</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Varun Warrier</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://unsplash.com/photos/person-holding-hands-yfmjALh1S6s" target="_blank">Matheus Ferrero</a></div></div></div><div class="field field-name-field-panel-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Researcher profile: Varun Warrier</div></div></div><div class="field field-name-field-panel-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><img alt="" src="/sites/www.cam.ac.uk/files/inner-images/photo2_forcraig.jpg" style="width: 800px; height: 533px;" /></p>&#13; &#13; <p>Varun Warrier is a PhD student at the Autism Research Centre, where he studies the genetics of autism and related traits. He moved to Cambridge in 2013 from India because of the Centre鈥檚 world-leading reputation.</p>&#13; &#13; <p>There are several key challenges in the field, he says. 鈥淔irst, we have identified only a fraction of the genes associated with autism. Second, no two autistic people are alike. Third, within the spectrum autistic people have different strengths and difficulties. Finally, those with a clinical diagnosis blend seamlessly into those in the population who don鈥檛 have a diagnosis but simply have a lot of autistic traits. We all have some autistic traits 鈥 this spectrum runs right through the population on a bell curve.鈥</p>&#13; &#13; <p>Although much of his work is computational, developing statistical tools to interrogate complex datasets that will enable him to answer biological questions, he also gets to meet many people with autism. 鈥淲hen I meet autistic people, I truly understand what's often said 鈥 no two autistic people are alike.鈥</p>&#13; &#13; <p>Warrier hopes his research will lead to a better understanding of the biology of autism, and that this will enable quicker and more accurate diagnosis. 鈥淏ut that's only one part of the challenge,鈥 he says. 鈥淯nderstanding the biology has its limits, and I hope that, in parallel, there will be better social policies to support autistic people.鈥澛</p>&#13; &#13; <p>Cambridge is an exciting place to be a researcher, he says. 鈥淚n Cambridge, there's always a local expert, so if you have a particular problem there usually is someone who can help you out. People here are not just thinking about what can be done to address the problems of today; they are anticipating problems that we will face in 20 years鈥 time, and are working to solve those.鈥</p>&#13; </div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Mon, 12 Mar 2018 01:07:28 +0000 cjb250 195942 at Genes influence ability to read a person鈥檚 mind from their eyes /research/news/genes-influence-ability-to-read-a-persons-mind-from-their-eyes <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/eyes.jpg?itok=LCefDscA" alt="" title="Eyes, Credit: Dboybaker" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>Twenty years ago, a team of scientists at the 探花直播 of Cambridge developed a test of 鈥榗ognitive empathy鈥 called the 鈥楻eading the Mind in the Eyes鈥 Test (or the Eyes Test, for short). This revealed that people can rapidly interpret what another person is thinking or feeling from looking at their eyes alone. It also showed that some of us are better at this than others, and that women on average score better on this test than men.</p> <p>Now, the same team, working with the genetics company 23andMe along with scientists from France, Australia and the Netherlands, report results from a new study of performance on this test in 89,000 people across the world. 探花直播majority of these were 23andMe customers who consented to participate in research. 探花直播results confirmed that women on average do indeed score better on this test.</p> <p>More importantly, the team confirmed that our genes influence performance on the Eyes Test, and went further to identify genetic variants on chromosome 3 in women that are associated with their ability to 鈥渞ead the mind in the eyes鈥.</p> <p> 探花直播study was led by Varun Warrier, a Cambridge PhD student, and Professors Simon Baron-Cohen, Director of the Autism Research Centre at the 探花直播 of Cambridge, and Thomas Bourgeron, of the 探花直播 Paris Diderot and the Institut Pasteur.</p> <p>Interestingly, performance on the Eyes Test in males was not associated with genes in this particular region of chromosome 3. 探花直播team also found the same pattern of results in an independent cohort of almost 1,500 people who were part of the Brisbane Longitudinal Twin Study, suggesting the genetic association in females is a reliable finding.</p> <p> 探花直播closest genes in this tiny stretch of chromosome 3 include LRRN1 (Leucine Rich Neuronal 1) which is highly active in a part of the human brain called the striatum, and which has been shown using brain scanning to play a role in cognitive empathy. Consistent with this, genetic variants that contribute to higher scores on the Eyes Test also increase the volume of the striatum in humans, a finding that needs to be investigated further.</p> <p>Previous studies have found that people with autism and anorexia tend to score lower on the Eyes Test. 探花直播team found that genetic variants that contribute to higher scores on the Eyes Test also increase the risk for anorexia, but not autism. They speculate that this may be because autism involves both social and non-social traits, and this test only measures a social trait.</p> <p>Varun Warrier says: 鈥淭his is the largest ever study of this test of cognitive empathy in the world. This is also the first study to attempt to correlate performance on this test with variation in the human genome. This is an important step forward for the field of social neuroscience and adds one more piece to the puzzle of what may cause variation in cognitive empathy.鈥澛</p> <p>Professor Bourgeron adds: 鈥淭his new study demonstrates that empathy is partly genetic, but we should not lose sight of other important social factors such as early upbringing and postnatal experience.鈥</p> <p>Professor Baron-Cohen says: 鈥淲e are excited by this new discovery, and are now testing if the results replicate, and exploring precisely what these genetic variants do in the brain, to give rise to individual differences in cognitive empathy. This new study takes us one step closer in understanding such variation in the population.鈥</p> <p><em><strong>Reference</strong><br /> Warrier, V et al. <a href="https://www.repository.cam.ac.uk/handle/1810/264268">Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition.</a> Molecular Psychiatry; 6 June 2017; DOI: 10.1038/MP.2017.122</em></p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Our DNA influences our ability to read a person鈥檚 thoughts and emotions from looking at their eyes, suggests a new study published in the journal <em>Molecular Psychiatry</em>.</p> </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">This is the first study to attempt to correlate performance on the Eye Test with variation in the human genome</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Varun Warrier</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.flickr.com/photos/demietrich/9243814710/in/photolist-f5QY4G-2VUE9z-5k3UNE-czFff-49nX6x-7yd83D-4B8Hb9-ajU5TJ-2jgxcZ-4xAWRX-6YVM9J-4HZ91r-4UyYZ-9jmUzB-3wRCrs-6XgLa2-2p4pFU-nnmCRM-yHNoM-a7GmXV-hxdQ7M-85AzsG-DXjGG-2sXfDH-59XnE9-4jC73-5sFfKy-67GbQn-n9xQB-4uN9Db-68XG6q-81BcWz-8PPq1d-f1zss3-mH9K6-6fC87k-4QNRJx-smeAd-6kSpMK-dS45ba-4i6CG1-7mv2X8-7CHcEs-9kxxH-rjUWr-8q8hHg-b1b22k-5Qg3KT-8v9v25-B5ZoE" target="_blank">Dboybaker</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Eyes</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br /> 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div><div class="field field-name-field-license-type field-type-taxonomy-term-reference field-label-above"><div class="field-label">Licence type:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/taxonomy/imagecredit/attribution">Attribution</a></div></div></div> Wed, 07 Jun 2017 10:59:54 +0000 cjb250 189462 at Elephants鈥 鈥榖ody awareness鈥 adds to increasing evidence of their intelligence /research/news/elephants-body-awareness-adds-to-increasing-evidence-of-their-intelligence <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/daleplotnik1.jpg?itok=v0WtLOTM" alt="Elephant body awareness tast" title="Elephant body awareness tast, Credit: Josh Plotnik/Rachel Dale" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>Self-awareness in both animals and young children is usually tested using the 鈥榤irror self-recognition test鈥 to see if they understand that the reflection in front of them is actually their own. Only a few species have so far shown themselves capable of self-recognition 鈥 great apes, dolphins, magpies and elephants. It is thought to be linked to more complex forms of perspective taking and empathy.</p>&#13; &#13; <p>Critics, however, have argued that this test is limited in its ability to investigate complex thoughts and understanding, and that it may be less useful in testing animals who rely less on vision than other species.</p>&#13; &#13; <p>One potential complement to the mirror test as a measure of self-understanding may be a test of 鈥榖ody-awareness鈥. This test looks at how individuals may recognise their bodies as obstacles to success in a problem-solving task. Such a task could demonstrate an individual鈥檚 understanding of its body in relation to its physical environment, which may be easier to define than the distinction between oneself and another demonstrated through success at the mirror test.</p>&#13; &#13; <p>To test for body-awareness in Asian elephants, Dr Josh Plotnik, visiting researcher at the 探花直播 of Cambridge, visiting assistant professor of psychology at Hunter College, City 探花直播 of New York and founder of conservation charity <a href="http://thinkelephants.org/">Think Elephants International</a>, devised a new test of self-awareness together with his colleague Rachel Dale (now a PhD student at the 探花直播 of Veterinary Medicine in Vienna). 探花直播new test was adapted from one in which children were asked to push a shopping trolley, but the trolley was attached to a mat on which they were standing.</p>&#13; &#13; <p>In the elephant version of the test, Plotnik and Dale attached a stick to a rubber mat using a rope; the elephants were then required to walk onto the mat, pick up the stick and pass it to an experimenter standing in front of them. 探花直播researchers wanted to investigate whether elephants understood the role of their bodies as potential obstacles to success in the task by observing how and when the animals removed themselves from the mat in order to exchange the stick. In one control arm of the test, the stick was unattached to the mat, meaning the elephant could pass the stick while standing on the mat.</p>&#13; &#13; <p> 探花直播results of the study, which was largely funded by a Newton International Fellowship from the Royal Society awarded to Dr Plotnik, are published today in the journal <em>Scientific Reports</em>.</p>&#13; &#13; <p>鈥淓lephants are well regarded as one of the most intelligent animals on the planet, but we still need more empirical, scientific evidence to support this belief,鈥 says Dale. 鈥淲e know, for example, that they are capable of thoughtful cooperation and empathy, and are able to recognise themselves in a mirror. These abilities are highly unusual in animals and very rare indeed in non-primates. We wanted to see if they also show 鈥榖ody-awareness鈥.鈥</p>&#13; &#13; <p>Plotnik and Dale found that the elephants stepped off the mat to pass the stick to the experimenter significantly more often during the test than during the control arm. Elephants stepped off the mat an average (mean) of around 42 out of 48 times during the test compared to just three times on average during the control.</p>&#13; &#13; <p>鈥淭his is a deceptively simple test, but its implications are quite profound,鈥 says Dr Plotnik. 鈥 探花直播elephants understood that their bodies were getting in the way, so they stepped aside to enable themselves to complete the task. In a similar test, this is something that young children are unable to understand until they are about two years old.</p>&#13; &#13; <p>鈥淭his implies that elephants may be capable of recognising themselves as separate from objects or their environment. This means that they may have a level of self-understanding, coupled with their passing of the mirror test, which is quite rare in the animal kingdom.鈥</p>&#13; &#13; <p>Species that have demonstrated a capacity for self-recognition in the mirror test all show varying levels of cooperative problem-solving, perspective taking and empathy, suggesting that 鈥榮elf-awareness鈥 may relate to effective cooperative-living in socially intelligent animals. A more developed self-understanding of how an individual relates to those around may underlie more complex forms of empathic perspective taking. It may also underlie how an individual targets help towards others in need. Both aspect are seen in studies of human children.</p>&#13; &#13; <p>Both self-awareness as demonstrated by the mirror test and body-awareness as demonstrated by the current study help scientists better understand how an animal鈥檚 understanding of self and of its place in the environment may impact social decision-making in the wild.</p>&#13; &#13; <p>Plotnik argues that studies such as this are important for helping increase our understanding of and appreciation for the behaviour and intelligence of animals. He also says that understanding elephant behaviour has important implications for the development of human/elephant conflict mitigation strategies in places like Thailand and India, where humans and elephants are competing for land. Only through careful consideration of both human and elephant needs can long-term solutions be sustainable.</p>&#13; &#13; <p>鈥 探花直播more we can understand about elephants鈥 behaviour, the more we can understand what their needs are, how they think and the strains they face in their social relationships,鈥 he says. 鈥淭his will help us if we are going to try to come up with viable long term solutions to the problems that these animals face in the wild, especially those that bring them into regular conflict with humans.鈥</p>&#13; &#13; <p><em><strong>Reference</strong><br />&#13; Dale, R, and Plotnik, JM. <a href="https://dx.doi.org/10.1038/srep46309">Elephants know when their bodies are obstacles to success in a novel transfer task.</a> Scientific Reports; 12 April 2017; DOI: 10.1038/srep46309</em></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Asian elephants are able to recognise their bodies as obstacles to success in problem-solving, further strengthening evidence of their intelligence and self-awareness, according to a new study from the 探花直播 of Cambridge.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"> 探花直播more we can understand about elephants鈥 behaviour, the more we can understand what their needs are, how they think and the strains they face in their social relationships</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Josh Plotnik</div></div></div><div class="field field-name-field-media field-type-file field-label-hidden"><div class="field-items"><div class="field-item even"><div id="file-124102" class="file file-video file-video-youtube"> <h2 class="element-invisible"><a href="/file/124102">Elephants demonstrate awareness of own bodies</a></h2> <div class="content"> <div class="cam-video-container media-youtube-video media-youtube-1 "> <iframe class="media-youtube-player" src="https://www.youtube-nocookie.com/embed/akjDRRgeUoI?wmode=opaque&controls=1&rel=0&autohide=0" frameborder="0" allowfullscreen></iframe> </div> </div> </div> </div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="http://thinkelephants.org/" target="_blank">Josh Plotnik/Rachel Dale</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Elephant body awareness tast</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Wed, 12 Apr 2017 09:00:06 +0000 cjb250 187362 at Does your empathy predict if you would stop and help an injured person? /research/news/does-your-empathy-predict-if-you-would-stop-and-help-an-injured-person <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/cyclist2.jpg?itok=588Zyi_8" alt="&#039;Injured&#039; cyclist on Trumpington Road" title="&amp;#039;Injured&amp;#039; cyclist on Trumpington Road, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>A team of psychologists at the 探花直播 of Cambridge has conducted a social psychology experiment to test the theory that an individual鈥檚 level of empathy influences their behaviour. 探花直播results of their preliminary study, dubbed 鈥 探花直播Trumpington Road Study鈥 and published in the journal <em>Social Neuroscience</em>, suggest that this theory is correct.<br /><br />&#13; In the experiment, one of the team posed as an injured person, sitting on the grass on Trumpington Road, one the main roads running through Cambridge, next to the Cambridge 探花直播 Botanic Garden. Next to the 鈥榠njured鈥 person was his upturned bicycle. Another member of the team was standing innocently across the road, watching to see if anyone was approaching from the side road of Brooklands Avenue.<br /><br />&#13; As soon as a member of the public approached the street corner, alone, and was about to turn into Trumpington Road, he gave a quiet signal to the 鈥榠njured鈥 person to start rubbing his ankle. 探花直播experiment had begun. 探花直播researcher across the street then noted if the passer-by stopped to ask the 鈥榠njured鈥 man if he was OK.<br /><br />&#13; Irrespective of whether passers-by stopped or not, once they had walked further up Trumpington Road, they were intercepted by a third researcher who told them she was conducting a 鈥榤emory鈥 experiment, inviting them to describe what they had seen along the road in the last few minutes. Various items had been left on the sidewalk (such as a scarf) to make this a plausible cover story. Those who agreed to take part were also asked to visit a website in their own time, and complete the Empathy Quotient (EQ) and Autism Spectrum Quotient (AQ) questionnaires, and were told they would receive a token payment of 拢6 for taking part.<br /><br />&#13; As the team predicted, EQ scores were higher in those who had stopped to help the injured cyclist, than in those who walked past him, presumably focused on their own agenda.<br /><br />&#13; 探花直播study was led by Richard Bethlehem, a Cambridge PhD student, and Professor Simon Baron-Cohen, Director of the Autism Research Centre at the 探花直播 of Cambridge. 37 (19 males, 18 females) completed both the EQ and also the AQ. They ranged in age from 18 to 77 years old.<br /><br />&#13; Interestingly, how many autistic traits a person recorded was not related to whether they stopped to help or not, suggesting that empathy is the key factor, not autistic traits. Nor did age predict who stopped or not. Of those who stopped to help, 80% were female.<br /><br />&#13; Richard Bethlehem said: 鈥淓xperimental studies are often confined to the lab, which means they lack 鈥榚cological validity鈥. In this novel study we tested if empathy scores predict if people will act altruistically in a real-world setting. Our results support the theory that people who do good are, at least partially, driven by empathy.鈥<br /><br />&#13; Dr Carrie Allison, a member of the team, commented: 鈥淗ow much empathy one has is itself a complex outcome of both biological factors and early upbringing and is a skill that can improve with development, learning, and practice.鈥<br /><br />&#13; Professor Baron-Cohen, author of <em>Zero Degrees of Empathy</em> and the Chair of Trustees of the Canadian-based charity 鈥淓mpathy for Peace鈥, said: 鈥淭his research is a first step towards understanding why some people may or may not stop to help a person in distress. Studies conducted 鈥榠n the wild鈥 are notoriously difficult to undertake, and even this small sample was derived from over 1,000 passers by. We will need to await a larger-scale replication. These results suggest that one factor that predicts which individuals will not stand idly by, is how many degrees of empathy they have.鈥<br /><br />&#13; 探花直播study was supported by the Autism Research Trust, the Medical Research Council, the Pinsent Darwin Trust, and the Cambridge Trust, and was conducted in association with the NIHR CLAHRC for Cambridgeshire and Peterborough NHS Foundation Trust.<br /><br /><em><strong>Reference</strong><br />&#13; Bethlehem, CA et al. <a href="https://dx.doi.org/10.1080/17470919.2016.1249944">Does empathy predict altruism in the wild?</a> Social Neuroscience; 19 Oct 2016; DOI: 10.1080/17470919.2016.1249944</em></p>&#13; &#13; <p>聽</p>&#13; &#13; <p>聽</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>If you see an injured person by the side of the road, would you stop and help them, or are you more likely to walk on by? What motivates people to do good in such a situation?聽</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">How much empathy one has is itself a complex outcome of both biological factors and early upbringing and is a skill that can improve with development, learning, and practice</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Carrie Allison</div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">&#039;Injured&#039; cyclist on Trumpington Road</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Mon, 31 Oct 2016 11:51:39 +0000 cjb250 180922 at Opinion: What your musical taste says about your personality /research/discussion/opinion-what-your-musical-taste-says-about-your-personality <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/discussion/151130headphones.jpg?itok=Tk1epgLS" alt="Headphones" title="Headphones, Credit: Jake Bellucci" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>We鈥檙e exposed to music for nearly 20% of <a href="https://onlinelibrary.wiley.com/doi/10.1111/j.1751-9004.2012.00434.x/abstract">our waking lives</a>. But much of our musical experience seems to be a mystery. Why does some music bring us to tears while other pieces make us dance? Why is it that the music that we like can make others agitated? And why do some people seem to have a natural ability to play music while others have difficulty carrying a tune? Science is beginning to show that these individual differences are not just random but are, in part, due to people鈥檚 personalities.</p>&#13; &#13; <p>My colleagues and I <a href="https://journals.plos.org:443/plosone/article?id=10.1371/journal.pone.0131151">have published</a> research showing that people鈥檚 musical preferences are linked to three broad thinking styles. Empathisers (Type E) have a strong interest in people鈥檚 thoughts and emotions. Systemisers (Type S) have a strong interest in patterns, systems and the rules that govern the world. And those who score relatively equally on empathy and systemising are classified as Type B for 鈥渂alanced鈥.</p>&#13; &#13; <p>Research from the <a href="https://journals.plos.org:443/plosone/article?id=10.1371/journal.pone.0102251">past decade</a> has shown that 95% of people can be classified into one of these three groups and that they predict a lot of human behaviour. For example, they can predict things such as whether someone studies maths and science, or humanities <a href="https://www.sciencedirect.com/science/article/pii/S1041608007000155">at university</a>. For the first time, we have shown that they can predict musical behaviour, too.</p>&#13; &#13; <h2>Matching music with thinking style</h2>&#13; &#13; <p>To study this phenomenon, we conducted <a href="https://journals.plos.org:443/plosone/article?id=10.1371/journal.pone.0131151">multiple studies</a> with over 4,000 participants. We took data on these participants鈥 thinking styles and asked them to listen to and indicate their preferences for up to 50 musical excerpts, representing a wide range of genres. Across these studies, we found that empathisers preferred mellow music that had low energy, sad emotions, and emotional depth, as heard in R&amp;B, soft rock, and singer-songwriter genres. For example, empathising was linked to preferences for 鈥淐ome Away With Me鈥 by Norah Jones and Jeff Buckley鈥檚 recording of 鈥淗allelujah鈥.</p>&#13; &#13; <p>聽</p>&#13; &#13; <figure><iframe allowfullscreen="" frameborder="0" height="260" src="https://www.youtube.com/embed/y8AWFf7EAc4?wmode=transparent&amp;start=0" width="440"></iframe></figure><p>聽</p>&#13; &#13; <p>On the other hand, systemisers preferred more intense music, as heard in hard rock, punk and heavy metal genres. Systemisers also preferred music with intellectual depth and complexity as heard in avant-garde classical genres. For example, systemizing was linked to preferences for Alexander Scriabin鈥檚 鈥淓tude opus 65 no 3鈥. Importantly, those who are Type B, had a tendency to prefer music that spans more of a range than the other two thinking styles.</p>&#13; &#13; <p>聽</p>&#13; &#13; <figure><iframe allowfullscreen="" frameborder="0" height="260" src="https://www.youtube.com/embed/pPvfq5H8PgQ?wmode=transparent&amp;start=0" width="440"></iframe></figure><p>聽</p>&#13; &#13; <p>In our <a href="http://www.doc.gold.ac.uk/~mas03dm/papers/Greenbergetal_PersonalityMusicalSophistication_2015.pdf">most recent study</a>, published in the Journal of Research of Personality, we found that people鈥檚 personality traits can also predict their musical ability, even if they don鈥檛 play an instrument. Our team worked with BBC Lab UK to recruit over 7,000 participants and assess them for five distinct personality dimensions: openness, conscientiousness, extroversion, agreeableness, and neuroticism/emotionality stability. We also asked them to conduct various tasks that measured their musical ability, including remembering melodies and picking out rhythms.</p>&#13; &#13; <p>We found that, next to musical training, the personality trait of openness was the strongest predictor of musical sophistication. People who score highly for openness are imaginative, have a wide range of interests, and are open to new ways of thinking and changes in their environment. Those who score low on openness (or who are 鈥渃losed鈥) are more set in their ways, prefer routine and the familiar, and tend to have more conventional values. We also found that extroverts who are often more talkative, assertive, and excitement-seeking had greater singing abilities.</p>&#13; &#13; <p>Furthermore, we could apply this even to people who did not currently play a musical instrument, meaning there are people who have a potential for musical talent but are entirely unaware of it.</p>&#13; &#13; <h2>Music therapy</h2>&#13; &#13; <p>These new findings tell us that from a person鈥檚 musical taste and ability, we can infer a range of information about their personality and the way that they think.</p>&#13; &#13; <p>This research shows there are factors beyond our awareness that shape our musical experiences. We hope that these findings can be of help to teachers, parents, and clinicians. Based on information about personality, educators can ensure that children with the potential for musical talent have the opportunity to learn a musical instrument. Music therapists can use information about thinking style to help tailor their therapies for clients, too.</p>&#13; &#13; <p>We are also interested in how knowledge gained from science can help children and adults on the autism spectrum who have difficulties with communication, as we recently wrote in the journal <a href="http://emusicology.org/article/view/4603">Empirical Musicology Review</a>. This could also help people process emotions after experiencing a psychological trauma and when grieving a loss. In fact, initial findings from our lab suggest that people who experienced a traumatic event in childhood engage with music quite differently in adulthood than those who did not experience a trauma.</p>&#13; &#13; <p><em>If you want to find out how you score on musical ability, preferences, and personality, you can take these tests at <a href="https://musicaluniverse.io/">www.musicaluniverse.org</a>.</em></p>&#13; &#13; <p><em><strong><span><a href="https://theconversation.com/profiles/david-m-greenberg-204317">David Greenberg</a>, PhD candidate, psychology, <a href="https://theconversation.com/institutions/university-of-cambridge-1283"> 探花直播 of Cambridge</a></span></strong></em></p>&#13; &#13; <p><em><strong>This article was originally published on <a href="https://theconversation.com/"> 探花直播Conversation</a>. Read the <a href="https://theconversation.com/what-your-musical-taste-says-about-your-personality-50492">original article</a>.</strong></em></p>&#13; &#13; <p><em> 探花直播opinions expressed in this article are those of the individual author(s) and do not represent the views of the 探花直播 of Cambridge.</em></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>David Greenberg (Department of Psychology) discusses how musical preferences are linked to thinking styles.</p>&#13; </p></div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.flickr.com/photos/jakescreations/69953132/in/photolist-7bwCu-nFS9i-4AxJJ8-ajxehR-6uzLyN-85JmbR-6SaZxn-9EcvFd-dRgtid-cwojCE-6FppEQ-23PhGJ-5UPajj-3wtLvH-97yhR9-futssE-6SStz9-qgsSmJ-9UTLtC-5nmEWP-4yFWkV-26dZo5-aEJeeH-dXqp7o-7KgDdP-mKjEYS-of9sHy-ouwR5F-5bxcwv-pA8s75-fYci6X-2hYGMj-5V2qF2-vY16-fvbKPX-cgVsy7-5LUJok-8EYNAC-9MY1Gf-akBP6s-buprei-cxbPvS-baFQGB-4iJJEk-5WsnPW-32mn8S-fAcvjc-dUuhoN-2dZvSS-9xRJvS" target="_blank">Jake Bellucci</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Headphones</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div><div class="field field-name-field-license-type field-type-taxonomy-term-reference field-label-above"><div class="field-label">Licence type:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/taxonomy/imagecredit/attribution-noncommerical">Attribution-Noncommerical</a></div></div></div> Mon, 30 Nov 2015 01:40:32 +0000 Anonymous 163442 at Musical tastes offer a window into how you think /research/news/musical-tastes-offer-a-window-into-how-you-think <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/deathangel.jpg?itok=0yvXRUjy" alt="Death Angel (cropped)" title="Death Angel (cropped), Credit: Damien Sisson DEATH ANGEL, Melbourne, Australia" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>In a study published today in the journal <em>PLOS ONE</em>, a team of psychologists show that your thinking style 鈥 whether you are an 鈥榚mpathizer鈥 who likes to focus on and respond to the emotions of others, or a 鈥榮ystemizer鈥 who likes to analyse rules and patterns in the world鈥攊s a predictor of the type of music you like.<br /><br />&#13; Music is a prominent feature of everyday life and nearly everywhere we go. It鈥檚 easy for us to know what types of music we like and don鈥檛 like. When shuffling songs on an iPod, it takes us only a few seconds to decide whether to listen or skip to the next track. However, little is known about what determines our taste in music.<br /><br />&#13; Researchers over the past decade have argued that musical preferences reflect explicit characteristics such as age and personality. For example, people who are open to new experiences tend to prefer music from the blues, jazz, classical, and folk genres, and people who are extraverted and 鈥榓greeable鈥 tend to prefer music from the pop, soundtrack, religious, soul, funk, electronic, and dance genres.<br /><br />&#13; Now a team of scientists, led by PhD student David Greenberg, has looked at how our 鈥榗ognitive style鈥 influences our musical choices. This is measured by looking at whether an individual scores highly on 鈥榚mpathy鈥 (our ability to recognize and react to the thoughts and feelings of others) or on 鈥榮ystemizing鈥 (our interest in understanding the rules underpinning systems such as the weather, music, or car engines) 鈥 or whether we have a balance of both.<br /><br />&#13; 鈥淎lthough people鈥檚 music choices fluctuates over time, we鈥檝e discovered a person鈥檚 empathy levels and thinking style predicts what kind of music they like,鈥 said David Greenberg from the Department of Psychology. 鈥淚n fact, their cognitive style 鈥 whether they鈥檙e strong on empathy or strong on systems 鈥 can be a better predictor of what music they like than their personality.鈥<br /><br />&#13; 探花直播researchers conducted multiple studies with over 4,000 participants, who were recruited mainly through the myPersonality Facebook app. 探花直播app asked Facebook users to take a selection of psychology-based questionnaires, the results of which they could place on their profiles for other users to see. At a later date, they were asked to listen to and rate 50 musical pieces. 探花直播researchers used library examples of musical stimuli from 26 genres and subgenres, to minimise the chances that participants would have any personal or cultural association with the piece of music.<br /><br />&#13; People who scored high on empathy tended to prefer mellow music (from R&amp;B, soft rock, and adult contemporary genres), unpretentious music (from country, folk, and singer/songwriter genres) and contemporary music (from electronica, Latin, acid jazz, and Euro pop). They disliked intense music, such as punk and heavy metal. In contrast, people who scored high on systemizing favoured intense music, but disliked mellow and unpretentious musical styles.<br /><br />&#13; 探花直播results proved consistent even within specified genres: empathizers preferred mellow, unpretentious jazz, while systemizers preferred intense, sophisticated (complex and avant-garde) jazz.<br /><br />&#13; 探花直播researchers then looked more in-depth and found those who scored high on empathy preferred music that had low energy (gentle, reflective, sensual, and warm elements), or negative emotions (sad and depressing characteristics), or emotional depth (poetic, relaxing, and thoughtful features). Those who scored high on systemizing preferred music that had high energy (strong, tense, and thrilling elements), or positive emotions (animated and fun features), and which also featured a high degree of cerebral depth and complexity.<br /><br />&#13; David Greenberg, a trained jazz saxophonist, says the research could have implications for the music industry. 鈥淎 lot of money is put into algorithms to choose what music you may want to listen to, for example on Spotify and Apple Music. By knowing an individual鈥檚 thinking style, such services might in future be able to fine tune their music recommendations to an individual.鈥<br /><br />&#13; Dr Jason Rentfrow, the senior author on the study says: 鈥淭his line of research highlights how music is a mirror of the self. Music is an expression of who we are emotionally, socially, and cognitively.鈥<br /><br />&#13; Professor Simon Baron-Cohen, a member of the team, added; 鈥淭his new study is a fascinating extension to the 鈥榚mpathizing-systemizing鈥 theory of psychological individual differences. It took a talented PhD student and musician to even think to pose this question. 探花直播research may help us understand those at the extremes, such as people with autism, who are strong systemizers.鈥<br /><br />&#13; Based on their findings, the following are songs that the researchers believe are likely to fit particular styles:</p>&#13; &#13; <h2>High on empathy</h2>&#13; &#13; <ul><li>Hallelujah 鈥 Jeff Buckley</li>&#13; <li>Come away with me 鈥 Norah Jones</li>&#13; <li>All of me 鈥 Billie Holliday</li>&#13; <li>Crazy little thing called love 鈥 Queen</li>&#13; </ul><h2>High on systemizing</h2>&#13; &#13; <ul><li>Concerto in C 鈥 Antonio Vivaldi</li>&#13; <li>Etude Opus 65 No 3 鈥 Alexander Scriabin</li>&#13; <li>God save the Queen 鈥 探花直播Sex Pistols</li>&#13; <li>Enter聽Sandman 鈥 Metallica</li>&#13; </ul><p>聽</p>&#13; &#13; <p>David Greenberg was funded by the聽Cambridge Commonwealth, European and International Trust and the Autism聽Research聽Trust during the period of this work.<br /><br /><em><strong>Reference</strong><br />&#13; Greenberg, DM, Baron-Cohen, S, Stillwell, DJ, Kosinski, M, &amp; Rentfrow, PJ. <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131151">Musical preferences are linked to cognitive styles</a>. PLOS ONE; 22 July 2015</em></p>&#13; &#13; <p><strong>Professor Simon Baron-Cohen will be speaking at the <a href="https://www.alumni.cam.ac.uk/events/alumni-festival-2015/is-autism-a-disorder"> 探花直播 of Cambridge Alumni Festival</a> on 26 September 2015.</strong></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Do you like your jazz to be Norah Jones or Ornette Coleman, your classical music to be Bach or Stravinsky, or your rock to be Coldplay or Slayer? 探花直播answer could give an insight into the way you think, say researchers from the 探花直播 of Cambridge.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">Although people鈥檚 music choices fluctuates over time, we鈥檝e discovered a person鈥檚 empathy levels and thinking style predicts what kind of music they like</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">David Greenberg</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.flickr.com/photos/gothicsanctuary/13906647763/in/photolist-nbTcT2-ovhMH5-nbTgUt-nbV67J-nbV5gA-n9QqAC-n9QvXL-n9Qonq-nbUXTq-n9QnGh-nbT4Ax-nbT56k-2U3yA-2U3BX-vvVcAT-vNp9ra-vvVcbK-86KS5z-vvMUYj-uRwVUD-vL6ewj-vL6e8J-vvMQxy-vvMPMf-aqiHpu-aqiH3y-n9QkTX-n9Qmww-n9QmxN-n9QoK8-nbUWA5-7XzYWV-7XA3F8-6yYMhN-6yYMMA-6yYMDQ-6yUFED-6yYMvY-4EYnT4-5wEggU-aqgiTk-c7Jgsj-aqgrHt-4EYnLz-4F3Cr3-4EYnqc-4F3DqC-4F3Dc7-4F3CQm-4EYnCp" target="_blank">Damien Sisson DEATH ANGEL, Melbourne, Australia</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Death Angel (cropped)</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="https://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="https://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div><div class="field field-name-field-license-type field-type-taxonomy-term-reference field-label-above"><div class="field-label">Licence type:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/taxonomy/imagecredit/attribution">Attribution</a></div></div></div> Wed, 22 Jul 2015 18:00:29 +0000 cjb250 155502 at Study confirms a gene linked to Asperger Syndrome and empathy /research/news/study-confirms-a-gene-linked-to-asperger-syndrome-and-empathy <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/puzzle.jpg?itok=PAjNX2ZG" alt="" title="Credit: John Hritz" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>A study聽published this month聽in the journal <a href="https://molecularautism.biomedcentral.com/articles/10.1186/2040-2392-4-48"><em>Molecular Autism</em></a> confirms previous research that people with Asperger Syndrome (AS) are more likely to carry specific variations in a particular gene. More strikingly, the study supports existing findings that the same gene is also linked to how much empathy typically shown by individuals in the general population.</p>&#13; &#13; <p> 探花直播research was carried out by a team of researchers led by Professor Baron-Cohen at the Autism Research Centre at Cambridge 探花直播. Asperger Syndrome is an autism spectrum condition. 探花直播researchers looked for sequence variations (called single nucleotide polymorphisms or SNPs) in the gene known as GABRB3 in a total of 530 adults - 118 people diagnosed with AS and 412 people without a diagnosis.</p>&#13; &#13; <p> 探花直播team found that certain SNPs in GABRB3 were significantly more common in people with AS. They also discovered that additional genetic variations in the same gene were linked to scores on an empathy measure called the Empathy Quotient (EQ) in the general population.</p>&#13; &#13; <p>AS is diagnosed when a person struggles with social relationships and communication, and shows unusually narrow interests and resistance to change, but has good intelligence and language skills. Most genetic studies of autistic spectrum conditions treat autism as if they are all very similar, whereas in reality there is considerable variation (e.g., in language level and intellectual ability).</p>&#13; &#13; <p>Rather than studying people on the autistic condition spectrum, this new study looked only people with AS, as a well-defined subgroup of individuals within this range.聽 探花直播researchers examined the gene GABRB3 which regulates the functioning of a neurotransmitter called gamma-aminobutyric acid (GABA) and which contains a number of SNPs that vary across the population.</p>&#13; &#13; <p> 探花直播volunteers were tested for 45 SNPs within this key gene. 探花直播team had previously found that SNPs in this gene were more common in adults with AS and also showed a relationship with empathy levels and tactile sensitivity (how sensitive people are to being touched) in the general population.</p>&#13; &#13; <p>Testing a new sample of volunteers who had not taken part in previous studies, the researchers found that three of the SNPs were again more common in adults with AS, and two different SNPs in the same gene were again related to empathy levels in the general population, confirming that the gene is involved in autism spectrum conditions.</p>&#13; &#13; <p>Professor Baron-Cohen said: 鈥淲e are excited that this study confirms that variation in GABRB3 is linked not just to AS but to individual differences in empathy in the population. Many candidate genes do not replicate across studies and across different samples, but this genetic finding seems to be a solid result. Research now needs to focus on where this gene is expressed in the brain in autism, and how it interacts with other genetic and non-genetic factors that cause AS.鈥</p>&#13; &#13; <p> 探花直播team was co-led by Dr Bhismadev Chakrabarti from the Department of Psychology at Reading 探花直播. He commented: 鈥淕enes play an important role in autism and Asperger Syndrome. This new study adds to evidence that GABRB3 is a key gene underlying these conditions. This gene is involved in the functioning of a neurotransmitter that regulates excitation and inhibition of nerve cell activity so the research gives us vital additional information about how the brain may develop differently in people with Asperger Syndrome.鈥</p>&#13; &#13; <p>Varun Warrier, who carried out the study as part of his graduate research at Cambridge 探花直播, added: 鈥 探花直播most important aspect of this research is that it points to common genetic variants in GABRB3 being involved in both AS and in empathy as a dimensional trait. Although GABRB3 is not the only gene to be involved in this condition and in empathy levels, we are confident that we have identified one of the key players. We are following this up by testing how much protein GABRB3 produces in the brain in autism, since a genetic finding of this kind becomes more explanatory when we can also measure its function.鈥</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Scientists have confirmed that variations in a particular gene play a key role in the autism spectrum condition known as Asperger Syndrome. They have also found that variations in the same gene are also linked to differences in empathy levels in the general population.聽</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">This study confirms that variation in GABRB3 is linked not just to Asperger Syndrome but to individual differences in empathy in the population.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Simon Baron-Cohen</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.flickr.com/photos/29818924@N00/409083204/in/photolist-C9EbG-DmMVY-JSVeX-PaQu3-RrQ1E-2MTaho-2UUGno-36YrR2-3bboEr-3cBdtd-3ekzr5-49eBa7-4aj6wU-4eMTQm-4fpHk2-4m28Z8-4q6yU4-4qaFj3-4r5tZ8-4riVxc-4rAM9f-58BJWE-59cK4X-59BFCr-5g2tSn-5g6PTY-5g6Qed-5oj57V-5sr428-5vWtga-5woxh8-5zQF6x-5JTESj-5K6JER-5KXvJc-5MX9iS-5S6Whs-5S6Whu-5SfK7D-5T78KJ-6chUJv-6r4zBu-6sYKTc-6NCGPm-77RyN3-7k44Xv-7oVHFt-7vMp9N-bzkEFh-7EVYj8-aSj57v" target="_blank">John Hritz</a></div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by-nc-sa/3.0/"><img alt="" src="/sites/www.cam.ac.uk/files/80x15.png" style="width: 80px; height: 15px;" /></a></p>&#13; &#13; <p>This work is licensed under a <a href="http://creativecommons.org/licenses/by-nc-sa/3.0/">Creative Commons Licence</a>. If you use this content on your site please link back to this page.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 17 Dec 2013 08:00:00 +0000 amb206 111062 at