ֱ̽ of Cambridge - human evolution /taxonomy/subjects/human-evolution en Genetic study reveals hidden chapter in human evolution /research/news/genetic-study-reveals-hidden-chapter-in-human-evolution <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/gettyimages-506356472-dp.jpg?itok=oPsh3EiG" alt="Plaster reconstructions of the skulls of human ancestors" title="Plaster reconstructions of the skulls of human ancestors, Credit: Jose A Bernat Bacete via Getty Images" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>Using advanced analysis based on full genome sequences, researchers from the ֱ̽ of Cambridge have found evidence that modern humans are the result of a genetic mixing event between two ancient populations that diverged around 1.5 million years ago. About 300,000 years ago, these groups came back together, with one group contributing 80% of the genetic makeup of modern humans and the other contributing 20%.</p> <p>For the last two decades, the prevailing view in human evolutionary genetics has been that Homo sapiens first appeared in Africa around 200,000 to 300,000 years ago, and descended from a single lineage. However, these latest <a href="https://www.nature.com/articles/s41588-025-02117-1">results</a>, reported in the journal <em>Nature Genetics</em>, suggest a more complex story.</p> <p>“ ֱ̽question of where we come from is one that has fascinated humans for centuries,” said first author Dr Trevor Cousins from Cambridge’s Department of Genetics. “For a long time, it’s been assumed that we evolved from a single continuous ancestral lineage, but the exact details of our origins are uncertain.”</p> <p>“Our research shows clear signs that our evolutionary origins are more complex, involving different groups that developed separately for more than a million years, then came back to form the modern human species,” said co-author Professor Richard Durbin, also from the Department of Genetics.</p> <p>While earlier research has already shown that Neanderthals and Denisovans – two now-extinct human relatives – interbred with Homo sapiens around 50,000 years ago, this new research suggests that long before those interactions – around 300,000 years ago – a much more substantial genetic mixing took place. Unlike Neanderthal DNA, which makes up roughly 2% of the genome of non-African modern humans, this ancient mixing event contributed as much as 10 times that amount and is found in all modern humans.</p> <p> ֱ̽team’s method relied on analysing modern human DNA, rather than extracting genetic material from ancient bones, and enabled them to infer the presence of ancestral populations that may have otherwise left no physical trace. ֱ̽data used in the study is from the 1000 Genomes Project, a global initiative that sequenced DNA from populations across Africa, Asia, Europe, and the Americas.</p> <p> ֱ̽team developed a computational algorithm called cobraa that models how ancient human populations split apart and later merged back together. They tested the algorithm using simulated data and applied it to real human genetic data from the 1000 Genomes Project.</p> <p>While the researchers were able to identify these two ancestral populations, they also identified some striking changes that happened after the two populations initially broke apart.</p> <p>“Immediately after the two ancestral populations split, we see a severe bottleneck in one of them—suggesting it shrank to a very small size before slowly growing over a period of one million years,” said co-author Professor Aylwyn Scally, also from the Department of Genetics. “This population would later contribute about 80% of the genetic material of modern humans, and also seems to have been the ancestral population from which Neanderthals and Denisovans diverged.”</p> <p> ֱ̽study also found that genes inherited from the second population were often located away from regions of the genome linked to gene functions, suggesting that they may have been less compatible with the majority genetic background. This hints at a process known as purifying selection, where natural selection removes harmful mutations over time.</p> <p>“However, some of the genes from the population which contributed a minority of our genetic material, particularly those related to brain function and neural processing, may have played a crucial role in human evolution,” said Cousins.</p> <p>Beyond human ancestry, the researchers say their method could help to transform how scientists study the evolution of other species. In addition to their analysis of human evolutionary history, they applied the cobraa model to genetic data from bats, dolphins, chimpanzees, and gorillas, finding evidence of ancestral population structure in some but not all of these.</p> <p>“What’s becoming clear is that the idea of species evolving in clean, distinct lineages is too simplistic,” said Cousins. “Interbreeding and genetic exchange have likely played a major role in the emergence of new species repeatedly across the animal kingdom.”</p> <p>So who were our mysterious human ancestors? Fossil evidence suggests that species such as Homo erectus and Homo heidelbergensis lived both in Africa and other regions during this period, making them potential candidates for these ancestral populations, although more research (and perhaps more evidence) will be needed to identify which genetic ancestors corresponded to which fossil group.</p> <p>Looking ahead, the team hopes to refine their model to account for more gradual genetic exchanges between populations, rather than sharp splits and reunions. They also plan to explore how their findings relate to other discoveries in anthropology, such as fossil evidence from Africa that suggests early humans may have been far more diverse than previously thought.</p> <p>“ ֱ̽fact that we can reconstruct events from hundreds of thousands or millions of years ago just by looking at DNA today is astonishing,” said Scally. “And it tells us that our history is far richer and more complex than we imagined.”</p> <p> ֱ̽research was supported by Wellcome. Aylwyn Scally is a Fellow of Darwin College, Cambridge. Trevor Cousins is a member of Darwin College, Cambridge.</p> <p> </p> <p><em><strong>Reference:</strong><br /> Trevor Cousins, Aylwyn Scally &amp; Richard Durbin. ‘<a href="https://www.nature.com/articles/s41588-025-02117-1">A structured coalescent model reveals deep ancestral structure shared by all modern humans</a>.’ Nature Genetics (2025). DOI: 10.1038/s41588-025-02117-1</em></p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Modern humans descended from not one, but at least 2 ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe.</p> </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">Our history is far richer and more complex than we imagined</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Aylwyn Scally</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.gettyimages.co.uk/detail/photo/reconstruction-with-plasters-to-royal-scale-of-royalty-free-image/506356472" target="_blank">Jose A Bernat Bacete via Getty Images</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Plaster reconstructions of the skulls of human ancestors</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="https://creativecommons.org/licenses/by-nc-sa/4.0/" rel="license"><img alt="Creative Commons License." src="/sites/www.cam.ac.uk/files/inner-images/cc-by-nc-sa-4-license.png" style="border-width: 0px; width: 88px; height: 31px;" /></a><br /> ֱ̽text in this work is licensed under a <a href="https://creativecommons.org/licenses/by-nc-sa/4.0/">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License</a>. Images, including our videos, are Copyright © ֱ̽ of Cambridge and licensors/contributors as identified. All rights reserved. We make our image and video content available in a number of ways – on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 18 Mar 2025 10:00:00 +0000 sc604 248776 at Study uncovers earliest evidence of humans using fire to shape the landscape of Tasmania /research/news/study-uncovers-earliest-evidence-of-humans-using-fire-to-shape-the-landscape-of-tasmania <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/emerald-swamp-copy.jpg?itok=dRRRlRu_" alt="Emerald Swamp, Tasmania" title="Emerald Swamp, Tasmania, Credit: Simon Haberle" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>A team of researchers from the UK and Australia analysed charcoal and pollen contained in ancient mud to determine how Aboriginal Tasmanians shaped their surroundings. This is the earliest record of humans using fire to shape the Tasmanian environment.</p> <p>Early human migrations from Africa to the southern part of the globe were well underway during the early part of the last ice age – humans reached northern Australia by around 65,000 years ago. When the first Palawa/Pakana (Tasmanian Indigenous) communities eventually reached Tasmania (known to the Palawa people as Lutruwita), it was the furthest south humans had ever settled.</p> <p>These early Aboriginal communities used fire to penetrate and modify dense, wet forest for their own use – as indicated by a sudden increase in charcoal accumulated in ancient mud 41,600 years ago.</p> <p> ֱ̽researchers say their <a href="https://doi.org/10.1126/sciadv.adp6579">results</a>, reported in the journal <em>Science Advances</em>, could not only help us understand how humans have been shaping the Earth’s environment for tens of thousands of years, but also help understand the long-term Aboriginal-landscape connection, which is vital for landscape management in Australia today.</p> <p>Tasmania currently lies about 240 kilometres off the southeast Australian coast, separated from the Australian mainland by the Bass Strait. However, during the last ice age, Australia and Tasmania were connected by a huge land bridge, allowing people to reach Tasmania on foot. ֱ̽land bridge remained until about 8,000 years ago, after the end of the last ice age, when rising sea levels eventually cut Tasmania off from the Australian mainland.</p> <p>“Australia is home to the world’s oldest Indigenous culture, which has endured for over 50,000 years,” said Dr Matthew Adeleye from Cambridge’s Department of Geography, the study’s lead author. “Earlier studies have shown that Aboriginal communities on the Australian mainland used fire to shape their habitats, but we haven’t had similarly detailed environmental records for Tasmania.”</p> <p> ֱ̽researchers studied ancient mud taken from islands in the Bass Strait, which is part of Tasmania today, but would have been part of the land bridge connecting Australia and Tasmania during the last ice age. Due to low sea levels at the time, Palawa/Pakana communities were able to migrate from the Australian mainland.</p> <p>Analysis of the ancient mud showed a sudden increase in charcoal around 41,600 years ago, followed by a major change in vegetation about 40,000 years ago, as indicated by different types of pollen in the mud.</p> <p>“This suggests these early inhabitants were clearing forests by burning them, in order to create open spaces for subsistence and perhaps cultural activities,” said Adeleye. “Fire is an important tool, and it would have been used to promote the type of vegetation or landscape that was important to them.”</p> <p> ֱ̽researchers say that humans likely learned to use fire to clear and manage forests during their migration across the glacial landscape of Sahul – a palaeocontinent that encompassed modern-day Australia, Tasmania, New Guinea and eastern Indonesia – as part of the extensive migration out of Africa.</p> <p>“As natural habitats adapted to these controlled burnings, we see the expansion of fire-adapted species such as Eucalyptus, primarily on the wetter, eastern side of the Bass Strait islands,” said Adeleye.</p> <p>Burning practices are still practiced today by Aboriginal communities in Australia, including for landscape management and cultural activities. However, using this type of burning, known as cultural burning, for managing severe wildfires in Australia remains contentious. ֱ̽researchers say understanding this ancient land management practice could help define and restore pre-colonial landscapes.</p> <p>“These early Tasmanian communities were the island’s first land managers,” said Adeleye. “If we’re going to protect Tasmanian and Australian landscapes for future generations, it’s important that we listen to and learn from Indigenous communities who are calling for a greater role in helping to manage Australian landscapes into the future.”</p> <p> ֱ̽research was supported in part by the Australian Research Council.</p> <p><em><strong>Reference:</strong><br /> Matthew A Adeleye et al. ‘<a href="https://doi.org/10.1126/sciadv.adp6579">Landscape burning facilitated Aboriginal migration into Lutruwita/Tasmania 41,600 years ago</a>.’ Science Advances (2024). DOI: 10.1126/sciadv.adp6579</em></p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Some of the first human beings to arrive in Tasmania, over 41,000 years ago, used fire to shape and manage the landscape, about 2,000 years earlier than previously thought.</p> </p></div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://researchportalplus.anu.edu.au/en/persons/simon-haberle" target="_blank">Simon Haberle</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Emerald Swamp, Tasmania</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="https://creativecommons.org/licenses/by-nc-sa/4.0/" rel="license"><img alt="Creative Commons License." src="/sites/www.cam.ac.uk/files/inner-images/cc-by-nc-sa-4-license.png" style="border-width: 0px; width: 88px; height: 31px;" /></a><br /> ֱ̽text in this work is licensed under a <a href="https://creativecommons.org/licenses/by-nc-sa/4.0/">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License</a>. Images, including our videos, are Copyright © ֱ̽ of Cambridge and licensors/contributors as identified. All rights reserved. We make our image and video content available in a number of ways – on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Fri, 15 Nov 2024 19:00:00 +0000 sc604 248551 at Canterbury suburbs were home to some of Britain’s earliest humans /stories/canterbury-suburbs-home-to-early-humans <div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Archaeological discoveries made on the outskirts of Canterbury, England, confirm the presence of early humans in southern Britain between 560,000 and 620,000 years ago, making it one of the earliest known Palaeolithic sites in northern Europe.</p> </p></div></div></div> Wed, 22 Jun 2022 06:00:00 +0000 ta385 232841 at Earliest human remains in eastern Africa dated to more than 230,000 years ago /stories/homosapiens <div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p> ֱ̽age of the oldest fossils in eastern Africa widely recognised as representing our species, Homo sapiens, has long been uncertain. Now, dating of a massive volcanic eruption in Ethiopia reveals they are much older than previously thought.</p> </p></div></div></div> Wed, 12 Jan 2022 15:28:02 +0000 sc604 229181 at DNA from 31,000-year-old milk teeth leads to discovery of new group of ancient Siberians /research/news/dna-from-31000-year-old-milk-teeth-leads-to-discovery-of-new-group-of-ancient-siberians <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/1_1.jpg?itok=F20YsCXV" alt=" ֱ̽two 31,000-year-old milk teeth found at the Yana Rhinoceros Horn Site in Russia which led to the discovery of a new group of ancient Siberians" title=" ֱ̽two 31,000-year-old milk teeth found at the Yana Rhinoceros Horn Site in Russia which led to the discovery of a new group of ancient Siberians, Credit: Russian Academy of Sciences" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p> ֱ̽finding was part of a wider study which also discovered 10,000-year-old human remains in another site in Siberia are genetically related to Native Americans – the first time such close genetic links have been discovered outside of the US.</p>&#13; &#13; <p> ֱ̽international team of scientists, led by Professor Eske Willerslev who holds positions at St John’s College, ֱ̽ of Cambridge, and is director of ֱ̽Lundbeck Foundation Centre for GeoGenetics at the ֱ̽ of Copenhagen, have named the new people group the ‘Ancient North Siberians’ and described their existence as ‘a significant part of human history’.</p>&#13; &#13; <p> ֱ̽DNA was recovered from the only human remains discovered from the era – two tiny milk teeth – that were found in a large archaeological site found in Russia near the Yana River. ֱ̽site, known as Yana Rhinoceros Horn Site (RHS), was found in 2001 and features more than 2,500 artefacts of animal bones and ivory along with stone tools and evidence of human habitation.</p>&#13; &#13; <p> ֱ̽discovery is published as part of a wider <a href="https://dx.doi.org/10.1038/s41586-019-1279-z">study</a> in <em>Nature</em> and shows the Ancient North Siberians endured extreme conditions in the region 31,000 years ago and survived by hunting woolly mammoths, woolly rhinoceroses, and bison.</p>&#13; &#13; <p>Professor Willerslev said: “These people were a significant part of human history, they diversified almost at the same time as the ancestors of modern-day Asians and Europeans and it’s likely that at one point they occupied large regions of the northern hemisphere.”</p>&#13; &#13; <p>Dr Martin Sikora, of ֱ̽Lundbeck Foundation Centre for GeoGenetics and first author of the study, added: “They adapted to extreme environments very quickly, and were highly mobile. These findings have changed a lot of what we thought we knew about the population history of northeastern Siberia but also what we know about the history of human migration as a whole.”</p>&#13; &#13; <p>Researchers estimate that the population numbers at the site would have been around 40 people with a wider population of around 500. Genetic analysis of the milk teeth revealed the two individuals sequenced showed no evidence of inbreeding which was occurring in the declining Neanderthal populations at the time.</p>&#13; &#13; <p> ֱ̽complex population dynamics during this period and genetic comparisons to other people groups, both ancient and recent, are documented as part of the wider study which analysed 34 samples of human genomes found in ancient archaeological sites across northern Siberia and central Russia.</p>&#13; &#13; <p>Professor Laurent Excoffier from the ֱ̽ of Bern, Switzerland, said: “Remarkably, the Ancient North Siberians people are more closely related to Europeans than Asians and seem to have migrated all the way from Western Eurasia soon after the divergence between Europeans and Asians.”</p>&#13; &#13; <p>Scientists found the Ancient North Siberians generated the mosaic genetic make-up of contemporary people who inhabit a vast area across northern Eurasia and the Americas – providing the ‘missing link’ of understanding the genetics of Native American ancestry.</p>&#13; &#13; <p>It is widely accepted that humans first made their way to the Americas from Siberia into Alaska via a land bridge spanning the Bering Strait which was submerged at the end of the last Ice Age. ֱ̽researchers were able to pinpoint some of these ancestors as Asian people groups who mixed with the Ancient North Siberians.</p>&#13; &#13; <p>Professor David Meltzer, Southern Methodist ֱ̽, Dallas, one of the paper’s authors, explained: “We gained important insight into population isolation and admixture that took place during the depths of the Last Glacial Maximum – the coldest and harshest time of the Ice Age - and ultimately the ancestry of the peoples who would emerge from that time as the ancestors of the indigenous people of the Americas.”</p>&#13; &#13; <p>This discovery was based on the DNA analysis of a 10,000-year-old male remains found at a site near the Kolyma River in Siberia. ֱ̽individual derives his ancestry from a mixture of Ancient North Siberian DNA and East Asian DNA, which is very similar to that found in Native Americans. It is the first time human remains this closely related to the Native American populations have been discovered outside of the US.</p>&#13; &#13; <p>Professor Willerslev added: “ ֱ̽remains are genetically very close to the ancestors of Paleo-Siberian speakers and close to the ancestors of Native Americans. It is an important piece in the puzzle of understanding the ancestry of Native Americans as you can see the Kolyma signature in the Native Americans and Paleo-Siberians. This individual is the missing link of Native American ancestry.”</p>&#13; &#13; <p><em><strong>Reference: </strong><br />&#13; Martin Sikora et al. '<a href="https://dx.doi.org/10.1038/s41586-019-1279-z"> ֱ̽population history of northeastern Siberia since the Pleistocene</a>.' Nature (2019). DOI: 10.1038/s41586-019-1279-z</em></p>&#13; &#13; <p><em>Originally published on the St John's College <a href="https://www.joh.cam.ac.uk/news">website</a>.</em></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Two children’s milk teeth buried deep in a remote archaeological site in north eastern Siberia have revealed a previously unknown group of people lived there during the last Ice Age.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">This individual is the missing link of Native American ancestry</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Eske Willerslev</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/" target="_blank">Russian Academy of Sciences</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even"> ֱ̽two 31,000-year-old milk teeth found at the Yana Rhinoceros Horn Site in Russia which led to the discovery of a new group of ancient Siberians</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; ֱ̽text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>. Images, including our videos, are Copyright © ֱ̽ of Cambridge and licensors/contributors as identified.  All rights reserved. We make our image and video content available in a number of ways – as here, on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Wed, 05 Jun 2019 17:00:00 +0000 hll43 205672 at Oldest genetic evidence of Hepatitis B virus found in ancient DNA from 4,500 year-old skeletons /research/news/oldest-genetic-evidence-of-hepatitis-b-virus-found-in-ancient-dna-from-4500-year-old-skeletons <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/2-crop.jpg?itok=r815B5Lb" alt="Mass burial of battle victims from the Xiongnu period in Omnogobi, Mongolia, from which scientists extracted ancient DNA from for the study." title="Mass burial of battle victims from the Xiongnu period in Omnogobi, Mongolia, from which scientists extracted ancient DNA from for the study., Credit: Alexey A. Kovalev" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>A pioneering study has identified the oldest evidence of HBV in the ancient remains and proved that viruses can become extinct. ֱ̽scientific significance of the research has been described as ‘truly remarkable’ and compared to the discovery of the first fossils.</p>&#13; &#13; <p>Today the Hepatitis B virus affects millions of people worldwide. In 2015 it was estimated that approximately 257 million people were chronically infected with HBV and 887,000 died due to associated complications such as liver cancer.</p>&#13; &#13; <p> ֱ̽new research, led by a group of academics at the Centre for Pathogen Evolution in the Department of Zoology at the ֱ̽ of Cambridge and the Centre for GeoGenetics at the ֱ̽ of Copenhagen, took genetic samples from skeletons across Europe and Asia from the Bronze Age to the Medieval period, and found 25 HBV-positive skeletons amongst the remains. In 12 of these skeletons, they found enough of the HBV genome to perform detailed analyses - the oldest of which was 4,500-years-old.</p>&#13; &#13; <p>From this data they were able to extract the genetic sequences of HBV that infected the individuals thousands of years ago.</p>&#13; &#13; <p> ֱ̽<a href="https://dx.doi.org/10.1038/s41586-018-0097-z">findings</a>, published in the journal <em>Nature</em><em>, </em>present new insights into the origins and evolution of HBV. ֱ̽genetic makeup of this strain could have implications for improving vaccines for HBV.</p>&#13; &#13; <p>Before this study, the oldest human viruses to be discovered were approximately 450-years- old but most are no more than 50-years-old. ֱ̽research now forms the oldest and largest datasets scientists have of ancient human viruses.</p>&#13; &#13; <p>Barbara Mühlemann, joint first author on the research paper and a graduate student at the ֱ̽ of Cambridge, said: “People have tried to unravel the history of HBV for decades - this study transforms our understanding of the virus and proves it affected people as far back as the Bronze Age. We have also shown that it is possible to recover viral sequences from samples of this age which will have much wider scientific implications.”</p>&#13; &#13; <p>Although HBV is a global health issue, little is known about its origin and evolution. As with many human viruses, this is largely due to a lack of historical evidence which has been difficult to locate and identify.</p>&#13; &#13; <p>Dr Terry Jones, joint first author who is based at the ֱ̽ of Cambridge’s Department of Zoology, explained: “Scientists mostly study modern virus strains and we have mainly been in the dark regarding ancient sequences – until now. It was like trying to study evolution without fossils. If we only studied the animals living today it would give us a very inaccurate picture of their evolution – it is the same with viruses.”</p>&#13; &#13; <p>Understanding more about HBV may now be possible. Showing that the virus has been circulating in humans since at least the Bronze Age is a big scientific advancement, as previous attempts to estimate how long the virus has infected humans have ranged from 400 years to 34,000 years.</p>&#13; &#13; <p> ֱ̽study was led by Professor Eske Willerslev, who holds positions both at St John’s College, ֱ̽ of Cambridge, and the ֱ̽ of Copenhagen.</p>&#13; &#13; <p>He said: “This data gives us an idea of how this virus behaves, and it provides us with a better idea of what is biologically possible in the future. Analysis of other ancient DNA samples may reveal further discoveries and this pioneering study could have huge implications for how the virus affects humans today.”</p>&#13; &#13; <p> ֱ̽research also shows the existence of ancient HBV genotypes in locations incompatible with their present-day distribution, contradicting previously-suggested geographical origins of the virus.</p>&#13; &#13; <p>Professor Willerslev initially suspected that it might be possible to find viruses in human remains based on previous research during his role at the ֱ̽ of Copenhagen. He approached Mühlemann and Jones who have specialised in identifying and studying the evolution of viruses.</p>&#13; &#13; <p> ֱ̽research approach the group used in the study, called ‘shotgun sequencing’, looks at all genetic material present in a sample, as opposed to ‘genome bio-capture’ which focuses only on the human genome.</p>&#13; &#13; <p>Professor Willerslev said: “This study is just the start. We’re talking about one virus here, but there are a lot of other viruses we could look for.”</p>&#13; &#13; <p><em><strong>Reference:</strong><br />&#13; Barbara Mühlemann et al. '<a href="https://dx.doi.org/10.1038/s41586-018-0097-z">Ancient Hepatitis B viruses from the Bronze Age to the Medieval period</a>.' Nature (2018). DOI: 10.1038/s41586-018-0097-z</em></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>An extinct strain of the human Hepatitis B virus (HBV) has been discovered in Bronze Age human skeletons found in burial sites across Europe and Asia.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">This study could have huge implications for how the virus affects humans today.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Eske Willerslev</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/" target="_blank">Alexey A. Kovalev</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Mass burial of battle victims from the Xiongnu period in Omnogobi, Mongolia, from which scientists extracted ancient DNA from for the study.</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; ֱ̽text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Wed, 09 May 2018 17:00:00 +0000 Anonymous 197152 at Height and weight evolved at different speeds in the bodies of our ancestors /research/news/height-and-weight-evolved-at-different-speeds-in-the-bodies-of-our-ancestors <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/option-2.jpg?itok=Q92yxiZx" alt="Femoral head bones of different hominin species. From top to bottom: Australopithecus afarensis (4-3 million years; ~40 kg, 130 cm); Homo ergaster (1.9-1.4 million years; 55-60 kg; ~165 cm); Neanderthal (200.000-30.000 years; ~70 kg; ~163 cm). " title="Femoral head bones of different hominin species. From top to bottom: Australopithecus afarensis (4-3 million years; ~40 kg, 130 cm); Homo ergaster (1.9-1.4 million years; 55-60 kg; ~165 cm); Neanderthal (200.000-30.000 years; ~70 kg; ~163 cm). , Credit: ֱ̽ of Cambridge" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>A wide-ranging new study of fossils spanning over four million years suggests that stature and body mass advanced at different speeds during the evolution of hominins – the ancestral lineage of which <em>Homo sapiens</em> alone still exist.</p>&#13; &#13; <p>Published today in the journal <a href="https://rsos.royalsocietypublishing.org/content/4/11/171339"><em>Royal Society: Open Science</em></a>, the research also shows that, rather than steadily increasing in size, hominin bodies evolved in “pulse and stasis” fluctuations, with some lineages even shrinking.</p>&#13; &#13; <p> ֱ̽findings are from the largest study of hominin body sizes, involving 311 specimens dating from earliest upright species of 4.4m years ago right through to the modern humans that followed the last ice age.</p>&#13; &#13; <p>While researchers describe the physical evolution of assorted hominin species as a “long and winding road with many branches and dead ends”, they say that broad patterns in the data suggest bursts of growth at key stages, followed by plateaus where little changed for many millennia.</p>&#13; &#13; <p> ֱ̽scientists were surprised to find a “decoupling” of bulk and stature around one and a half million years ago, when hominins grew roughly 10cm taller but would not consistently gain any heft for a further million years, with an average increase of 10-15kgs occurring around 500,000 years ago.</p>&#13; &#13; <p>Before this event, height and weight in hominin species appeared to evolve roughly “in concert”, say the authors of this first study to jointly analyse both aspects of body size over millions of years. </p>&#13; &#13; <p>“An increase solely in stature would have created a leaner physique, with long legs and narrow hips and shoulders. This may have been an adaptation to new environments and endurance hunting, as early <em>Homo </em>species left the forests and moved on to more arid African savannahs,” says lead author Dr Manuel Will from Cambridge’s Department of Archaeology, and a Research Fellow at Gonville &amp; Caius College.     </p>&#13; &#13; <p>“ ֱ̽higher surface-to-volume ratio of a tall, slender body would be an advantage when stalking animals for hours in the dry heat, as a larger skin area increases the capacity for the evaporation of sweat.</p>&#13; &#13; <p>“ ֱ̽later addition of body mass coincides with ever-increasing migrations into higher latitudes, where a bulkier body would be better suited for thermoregulation in colder Eurasian climates,” he says.</p>&#13; &#13; <p>However, Dr Will points out that, while these are valid theories, vast gaps in the fossil record continue to mask absolute truths. In fact, Will and colleagues often had to estimate body sizes from highly fragmented remains – in some cases from just a single toe bone.</p>&#13; &#13; <p> ֱ̽study found body size to be highly variable during earlier hominin history, with a range of differently shaped species: from broad, gorilla-like <em>Paranthropus </em>to the more wiry or ‘gracile’ <em>Australopithecus afarensis</em>. Hominins from four million years ago weighed a rough average of 25kg and stood at 125-130cm.  </p>&#13; &#13; <p>As physicality morphs over deep time, increasingly converging on larger body sizes, the scientists observe three key “pulses” of significant change.</p>&#13; &#13; <p> ֱ̽first occurs with the dawn of our own defined species bracket, <em>Homo</em>, around 2.2-1.9m years ago. This period sees a joint surge in both height (around 20 cm) and weight (between 15-20kg).</p>&#13; &#13; <p>Stature then separated from heft with a height increase alone of 10cm between 1.4-1.6m years ago, shortly after the emergence of Homo erectus. “From a modern perspective this is where we see a familiar stature reached and maintained. Body mass, however, is still some way off,” explains Will.        </p>&#13; &#13; <p>It’s not until a million years later (0.5-0.4m years ago) that consistently heavier hominins appear in the fossil record, with an estimated 10-15kg greater body mass signalling adaptation to environments north of the Mediterranean.</p>&#13; &#13; <p>“From then onwards, average body height and weight stays more or less the same in the hominin lineage, leading ultimately to ourselves,” says Will.</p>&#13; &#13; <p>There are, however, a couple of exceptions to this grand narrative: <em>Homo naledi </em>and <em>Homo floresiensis</em>. Recently discovered remains suggest these species swam against the tide of increasing body size through time.</p>&#13; &#13; <p>“They may have derived from much older small-bodied ancestors, or adapted to evolutionary pressures occurring in small and isolated populations,” says Will. <em>Floresiensis </em>was discovered on an Indonesian island.</p>&#13; &#13; <p>“Our study shows that, other than these two species, hominins that appear after 1.4m years ago are all larger than 140cm and 40kg. This doesn’t change until human bodies diversify again in just the last few thousand years.”</p>&#13; &#13; <p>“These findings suggest extremely strong selective pressures against small body sizes which shifted the evolutionary spectrum towards the larger bodies we have today.”</p>&#13; &#13; <p>Will and colleagues say evolutionary pressures that may have contributed include ‘cladogenesis’: the splitting of a lineage, with one line – the smaller-bodied one, in this case – becoming extinct, perhaps as a result of inter-species competition.</p>&#13; &#13; <p>They also suggest that sexual dimorphism – the physical distinction between genders, with females typically smaller in mammals – was more prevalent in early hominin species but then steadily ironed out by evolution.</p>&#13; &#13; <p>Study co-author Dr Jay Stock, also from Cambridge’s Department of Archaeology, suggests this growth trajectory may continue.</p>&#13; &#13; <p>“Many human groups have continued to get taller over just the past century. With improved nutrition and healthcare, average statures will likely continue to rise in the near future. However, there is certainly a ceiling set by our genes, which define our maximum potential for growth," Stock says.</p>&#13; &#13; <p>“Body size is one of the most important determinants of the biology of every organism on the planet,” adds Will. “Reconstructing the evolutionary history of body size has the potential to provide us with insights into the development of locomotion, brain complexity, feeding strategies, even social life.”</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p> ֱ̽largest study to date of body sizes over millions of years finds a “pulse and stasis” pattern to hominin evolution, with surges of growth in stature and bulk occurring at different times. At one stage, our ancestors got taller around a million years before body mass caught up.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">Body size is one of the most important determinants of the biology of every organism on the planet</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Manuel Will</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/" target="_blank"> ֱ̽ of Cambridge</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Femoral head bones of different hominin species. From top to bottom: Australopithecus afarensis (4-3 million years; ~40 kg, 130 cm); Homo ergaster (1.9-1.4 million years; 55-60 kg; ~165 cm); Neanderthal (200.000-30.000 years; ~70 kg; ~163 cm). </div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; ֱ̽text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Wed, 08 Nov 2017 00:33:01 +0000 fpjl2 192972 at ֱ̽Monuments Men of Libya /research/discussion/the-monuments-men-of-libya <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/discussion/170227haua-fteahcredit-cyrenaica-prehistory-project.jpg?itok=li0Tq1Wv" alt="Members of the project at the end of the 2012 season" title="Members of the project at the end of the 2012 season, Credit: Cyrenaica Prehistory Project" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>True heroes, generous hearts: these are the Libyan archaeologists who, with Daesh at their heels, have accomplished the feat of completing the excavation of the Haua Fteah cave in Cyrenaica, one of the most important prehistoric sites of all Africa. When, in 2013, the team of international researchers involved at the site was forced to suspend work, nine Libyan archeologists - two women and seven men - successfully completed the excavation by themselves, securing its secrets for posterity. Thus the history of human population along the North African coast over the last 100 thousand years can now be written.</p> <p>Haua Fteah is, in fact, the largest karst cave in the Mediterranean (measuring 80 x 20 metres) and is open to the sea a short distance from the city of Susa, the ancient Apollonia.  It is a sort of natural hangar, inhabited uninterruptedly by humans from prehistoric times until the present. Investigated for the first time between 1951 and 1955 by Charles McBurney - an archaeologist from the ֱ̽ of Cambridge - the same university resumed the research in 2007 under the direction of Professor Graeme Barker, in collaboration with the Libyan Department of Antiquities and an international team of scholars, including myself.</p> <p>Beginning at the earliest levels, at about 15 meters below the current surface and relating to the Middle Palaeolithic, the cave takes us on a breathtaking journey through time. We first move through the levels dating back to 70,000 years ago where the only human remains found so far at the site - two fragments of <em>Homo sapiens</em> lower jaw - were uncovered: a moving testimony to the arrival of our ancestors along the North African coast. We can then examine the layers of the Upper Paleolithic on our way to the Neolithic, when the first species of domesticated animals and plants of the Levantine regions made their appearance in North Africa. Continuing our journey towards the surface, through layers dating from the Classical Period and thence more recent ones, we arrive at the present day. Like a wonderful freeze frame which has lasted thousands of years, the cave is still in use to this very day - as a livestock shelter - by families of shepherds.  It is greatly respected by the local population.</p> <p><img alt="" src="/sites/www.cam.ac.uk/files/inner-images/170227_haua-fteah_2_credit-cyrenaica-prehistory-project.jpg" style="width: 100%; height: 100%;" /></p> <p>Despite the instability that has followed the collapse, in 2011, of the Gaddafi regime in Libya, we continued to work at Haua Fteah - albeit with considerable difficulty - until September 2012 when the US Ambassador to Libya, Chris Stevens, was assassinated in Benghazi. ֱ̽terrible news reached us while we were actually digging in the cave. We were struck by a deep sense of loss, but also with concern for our own safety. We left Libya a few days later and, after months of indecision and another very brief campaign in 2013, Graeme Barker reluctantly decided to suspend the excavation. Daesh had definitively taken control of the city of Derna, just 60 kilometers east of Haua Fteah, and the risk to our safety was really too great.</p> <p>However, our Libyan colleagues continued to monitor the massive open trench, and a short while later they informed us that its walls, exposed since 2007, were not going to last for long. To safeguard and bring to a conclusion the work of years, the excavation had to be completed as soon as possible. “We can do it ourselves,” said Ahmad Saad Emrage, archaeologist at the ֱ̽ of Benghazi. “We can still work safely enough. We will be accurate and fast.” So, without any delay, the ‘command’ of operations fell to Ahmad and his team of local archaeologists: Fadl Abdulazeez, Akram Alwarfalli, Moataaz Azwai, Saad Buyadem, Badr Shamata, Asma Sulaiman, Reema Sulaiman and Aiman ​​Alareefi.</p> <p><img alt="" src="/sites/www.cam.ac.uk/files/inner-images/170227_haua-fteah_4_credit-cyrenaica-prehistory-project.jpg" style="width: 250px; height: 250px; float: right;" /></p> <p>Who are these ‘Fantastic 9’? They are, first and foremost, passionate archaeologists and serious professionals. Ahmad and Fadl are the ‘fathers’ of the group, always ready to guide and encourage the younger ones; then there is Moataz, the tireless ‘gentle giant’; then two young daredevils, Akram and Saad, who, after a day of excavation, love to dive from the beautiful cliffs of Lathrun; also Badr and Aiman, who make sure the rest of the troop always has tea in their cups and sheesha to puff on; and then the two sisters, Aasma and Reema, who have iron will. Nine different individuals, nine different histories, united by an immense passion for their homeland, Libya, and by a single unwavering desire: to save their country and its history.</p> <p> ֱ̽first excavation campaign began on May 9th 2015 and was supposed to last for two months, but it was suspended after only four weeks. Ahmad told me that “after work started with no particular problem, the situation had rapidly deteriorated. Local sources had reported to us that Daesh militants had recently been seen in the Susa area. When passing through the town we would often hear gunfire and screams. We were afraid, but we did not want to stop. During the raids against the Daesh positions in Derna, Libyan air force planes and helicopters flew over the cave. We were by no means certain that they were all aware of our presence in the area, and, for fear of being mistaken for terrorists, we would run to take shelter in the back of the cave every time we heard the noise of an approaching aircraft. I remember one day when I was carrying the long plastic tube we used to store the stratigraphy drawings of the excavation over my shoulder; on hearing the sound of an approaching helicopter, Fadl grabbed the tube and threw it away from us, for fear it could be mistaken for a rocket launcher. We were extremely tense, and when the helicopter finally moved away, we looked at each other and burst into laughter.”</p> <p>“We were increasingly afraid but we continued to work. One day, however, a friend came running, shouting that the night before he had seen masked men in the vicinity of the cave, almost certainly Daesh militiamen. And shortly afterwards the Susa police arrived and forced us to stop work. It was not easy to convince the boys that we could not go on. ‘We can still do it - they kept repeating – we’ll be even more careful and fast’.  Reluctantly, however, we collected the equipment and left the cave.”</p> <p>But that was not the end by any means. Two months later, thanks to the liberation of Derna from Daesh militia, the 'Fantastic 9' returned to the cave and finally managed to complete the excavation. “Do not call us heroes,” Ahmad exclaimed when I told him that I would recount their adventure. “We just did what had to be done, as archaeologists and as Libyans.” However, in a country like Libya that sees its archaeological heritage so dramatically at risk, our colleagues’ achievement was exceptional in its significance: it showed that the Libyans have not given up, that they wish to reclaim their own cultural heritage and determine its fate themselves.</p> <p><em>Inset images: Top: the Haua Fteah trench (credit: Cyrenaica Prehistory Project). Bottom: Saad Buyadem and Fadl Abdulazeez (credit: Cyrenaica Prehistory Project).</em></p> <p><em>Dr Giulio Lucarini is a Leverhulme Research Fellow at the McDonald Institute for Archaeological Research in Cambridge. Excavation at Haua Fteah has been principally funded by the European Research Council, with supplementary funding from the Society of Libyan Studies, the project’s sponsor.</em></p> <p><em>This article was first published in <a href="https://archeostoriejpa.eu/">Archeostorie</a>. Journal of Public Archaeology.</em></p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>With Daesh militia at their heels, a handful of brave Libyan archaeologists completed the excavation of the Haua Fteah cave in Cyrenaica, North Africa. Cambridge archaeologist Dr Giulio Lucarini tells their story.</p> </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">“We can do it ourselves,” said Ahmad Saad Emrage, archaeologist at the ֱ̽ of Benghazi. “We can still work safely enough. We will be accurate and fast.” </div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/" target="_blank">Cyrenaica Prehistory Project</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Members of the project at the end of the 2012 season</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br /> ֱ̽text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 28 Feb 2017 08:20:20 +0000 Anonymous 185522 at