探花直播 of Cambridge - postgraduate /taxonomy/subjects/postgraduate en New PhD funding programme launched /stories/PhD-funding <div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Trinity College and the 探花直播 of Cambridge鈥檚 new 拢48 million programme enabling fully-funded PhDs has been launched.</p> </p></div></div></div> Mon, 11 Nov 2024 12:17:11 +0000 ps748 248545 at Black researchers shaping the future /research/features/black-researchers-shaping-the-future <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/features/tom-montage-3for-website.jpg?itok=C8jEmuXZ" alt=" 探花直播 of Cambridge researchers" title=" 探花直播 of Cambridge researchers, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="/stories/black-history-month-researchers">Read the full story here</a></p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>As the UK marks Black History Month,聽researchers from across the 探花直播 talk about their route to Cambridge, their inspiration and their motivation.</p>&#13; </p></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even"> 探花直播 of Cambridge researchers</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>. Images, including our videos, are Copyright 漏 探花直播 of Cambridge and licensors/contributors as identified.聽 All rights reserved. We make our image and video content available in a number of ways 鈥 as here, on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Wed, 10 Oct 2018 09:32:12 +0000 ta385 200362 at Conservationists gather to mark International Women's Day /news/conservationists-gather-to-mark-international-womens-day <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/news/whale-crop.jpg?itok=UaupAm4q" alt="" title="Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p> 探花直播event, jointly organised by the Museum and the Cambridge Conservation Forum鈥檚 Women in Conservation Leadership Network, was held to mark International Women鈥檚 Day and included a keynote lecture by Professor Rebecca Kilner from Cambridge鈥檚 Department of Zoology.</p> <p>Kilner said; 鈥淓vents like this are important for showing the next generation that anyone with a spark for science can work in science subjects. They are designed to excite and encourage young people to pursue their interests - and not to be held back by their gender, race or background.鈥</p> <p> 探花直播Museum welcomed over 100 visitors to the event, which included 鈥榤eet the scientist鈥 stalls, a poster exhibition, and a sneak-peek at the newly refurbished Whale Hall.</p> <p>More than 30 women working in different scientific fields took part, from organisations including the United Nations鈥 Environment World Conservation Monitoring Centre, the RSPB and the International Union for the Conservation of Nature. They were joined by staff and volunteers from the museum, and Cambridge postgraduate students.</p> <p>Dr Rosalyn Wade, the Museum鈥檚 Interpretation and Learning Officer, helped to coordinate the event. She said; 鈥淎 key role for the Museum is engaging with the public and raising awareness of work in biological and environmental sciences.</p> <p>鈥淚t鈥檚 important to raise awareness of the different kinds of careers available in scientific fields. A number of our visitors were GCSE and A-Level students, and it was a great opportunity for them to see the range of roles that might be available to them in the future.</p> <p>鈥淲e also had lots of new mums who are thinking about a career change and were interested to learn more about different areas. It was great to see such a diverse range of people.鈥</p> <p> 探花直播Museum has undergone a massive redevelopment, and will officially re-open to the public on 23 June.</p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Scientists from around the world gathered at the Museum of Zoology yesterday to celebrate and promote the work of women in conservation.</p> </p></div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br /> 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Fri, 09 Mar 2018 16:08:16 +0000 ed515 195972 at Postgraduate Open Day 2017 - meet our postgrads /news/postgraduate-open-day-2017-meet-our-postgrads <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/news/img0530croppedforweb.jpg?itok=qhyJjV97" alt="Jerelle Joseph, PhD in computational chemistry at Churchill College (Gates Scholar)" title="Jerelle Joseph, PhD in computational chemistry at Churchill College (Gates Scholar), Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>These students walk in the footsteps of giants: Francis Crick, Elizabeth Blackburn, Stephen Hawking, Iris Murdoch and Eric Hobsbawm all pursued PhD research here.</p> <p>We thought you might like the opportunity to <a href="/stories/postgraduate-open-day-2017">meet a few of them</a> ...</p> </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Nearly 10,000 <a href="/stories/postgraduate-open-day-2017">postgraduate students</a> from more than 250 countries, working in countless different subject areas, contribute to Cambridge鈥檚 thriving postgraduate community.</p> </p></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Jerelle Joseph, PhD in computational chemistry at Churchill College (Gates Scholar)</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br /> 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p> </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div><div class="field field-name-field-license-type field-type-taxonomy-term-reference field-label-above"><div class="field-label">Licence type:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/taxonomy/imagecredit/attribution-noncommercial-sharealike">Attribution-Noncommercial-ShareAlike</a></div></div></div> Fri, 03 Nov 2017 16:05:42 +0000 sjr81 192912 at Postgraduate Pioneers 2017 #5 /news/postgraduate-pioneers-2017-5 <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/news/eleanor-photocropforweb.gif?itok=16IipyzW" alt="Eleanor Barnett, PhD student" title="Eleanor Barnett, PhD student, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div><strong>Fifth in the series is Eleanor Barnett, a historian examining the relationship between food and religious change during the European Reformations.</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My research sets out to聽</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>Focusing on England and Italy, I look at how food was used in worship both within and outside of the church, how religion shaped people鈥檚 ideas of what was healthy to eat, and how religion impacted on the ways and material environments in which people ate in everyday life.聽聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>One of the most important theological changes of the Reformation was the Protestant rejection of the Catholic belief in transubstantiation. I鈥檓 interested in how this worked out in what people were actually eating in the Communion.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>In England, Elizabeth I wrote in her Prayer Book of 1559 that the Communion bread should be table bread of the best quality, but in the same year the Queen鈥檚 Injunctions state that the bread should be more like the pre-Reformation Catholic wafer so that 鈥榯he more reverence to be given to these holy mysteries鈥. She called for the traditional stamp to be removed from the wafer and for the wafer to be made a little wider and thicker.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>This is interesting because it shows that whilst, in accordance with a changed understanding of grace and salvation in Protestant theology, there was a drive in Elizabethan England to remove material things that could be worshiped, there remained a desire to make sure that what you were commemorating was still reflected in material properties. So in this case, the bread still had to be in some way special.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>At the start of Elizabeth鈥檚 reign, attempts were made to enforce the Injunctions but by the 1570s, it became clear that table bread was more commonly used.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My Motivation</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div> 探花直播most important thing for me is to understand how people experienced religion in the early modern period. More specifically, I hope to get across that people in the past were not intellectualized beings always concerned with theology, but were interacting with their bodies and the material environment every day in ways that reflected or enforced their religious identity. Food is a really useful way to explore the lived experience of what it meant to be a Protestant or a Catholic in this period.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>Everyone has to eat so food is a great way for us in the twenty-first century to connect with people in the past on a human level. Food was and remains so central to human identities.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I鈥檓 really interested in public history initiatives and I鈥檓 an Editor for the blog, <a href="https://doinghistoryinpublic.org/">Doing History in Public</a>聽so my research topic and philosophy as a historian go hand-in-hand.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My best days</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>A highlight for me has been looking at the really unusual and significant Elizabethan records at King鈥檚 College, Cambridge. These record day-by-day what was being eaten in the College. This is invaluable evidence for me because its shows how far people were adhering to the Church鈥檚 instructions regarding food, in particular what could be consumed on the weekly Fish Days, Lent and religious feast days.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I discovered that throughout the period, King鈥檚 College adhered to eating fish on Friday and Saturday and avoiding meat during Lent. There were, however, times in Lent when the College was prepared to celebrate. In 1560, the Feast of Annunciation occurred during Lent and the College hosted a really big feast, five times more expensive than a normal Monday.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I have also seen significant changes in the Elizabethan period reflected in what was happening at King鈥檚. For instance, by 1576 the College had abandoned the Feast of St Barnabas in accordance with the New Calendar, but started celebrating the Queen鈥檚 Day on 17 November to celebrate Elizabeth鈥檚 coronation.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>I hope my work will lead to</strong>聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>My PhD research will contribute to our understanding of what it meant to be a Protestant and a Catholic in Reformation Europe, through exploring the embodied, sensory, and everyday religious experience of eating.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>By taking a comparative approach, I hope that this theme will shed new light on the differences between Catholic and Protestant identities, and ultimately comment on the nature of religious change in the Reformation periods.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>&#13; <div><strong>It had to be Cambridge because</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I am lucky enough to have two fantastic historians as my supervisors, <a href="https://www.hist.cam.ac.uk/people/professor-craig-muldrew">Professor Craig Muldrew</a> and <a href="https://www.hist.cam.ac.uk/people/professor-ulinka-rublack-fba">Professor Ulinka Rublack</a>, and to be further supported by a brilliant wider team of historians. We meet in seminars every week and the graduate students also have workshops where you can share ideas and hear papers.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>At the same time, at Cambridge you鈥檙e given the freedom to grow as an independent researcher and to develop new skills through practical experience - I am currently improving my Italian and paleographical skills by researching in the Venetian archives!聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I particularly like the emphasis on inter-disciplinary work聽at Cambridge, so for me that means I can speak to art historians and scientists about how the body functions, how it was thought to function in the past, and how this might affect food and consumption practices in the Reformation period.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>It鈥檚 an everyday inspiration to be surrounded by art and architecture from the period you are studying, not least in my own College, Christ鈥檚. But Cambridge also plays a much more active role in my research because some of the Colleges hold such rich early modern records.</div>&#13; </div>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>With our Postgraduate Open Day fast-approaching (3 November), we introduce five PhD candidates who are already making waves at Cambridge.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">Food was and remains so central to human identities.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Eleanor Barnett, PhD student</div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Eleanor Barnett, PhD student</div></div></div><div class="field field-name-field-panel-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Postgraduate Open Day</div></div></div><div class="field field-name-field-panel-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information about the 探花直播's Postgraduate Open Day on 3rd November 2017 and to book to attend, <a href="https://www.postgraduate.study.cam.ac.uk/events">please click here</a>.</p>&#13; </div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Thu, 02 Nov 2017 10:00:00 +0000 ta385 192832 at Postgraduate Pioneers 2017 #4 /news/postgraduate-pioneers-2017-4 <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/news/yesimweb-imagecrop.gif?itok=sGCff9WL" alt="Yesim Yaprak Yildiz, PhD student" title="Yesim Yaprak Yildiz, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><strong>Fourth in the series is Yesim Yaprak Yildiz, a sociologist exploring the relationship between political violence, truth and reconciliation with a focus on Turkey.</strong></p>&#13; &#13; <p><strong>My research sets out to聽</strong></p>&#13; &#13; <p>My passion is to understand the relationship between truth and justice, more specifically whether revelation of truth about an atrocity would lead to justice. I set out to answer this question by examining the social and political effects of public confessions of state officials on past atrocities against civilians. I focus聽on Turkey and state violence against the Kurds in the 1990s.聽</p>&#13; &#13; <p><strong>My motivation</strong></p>&#13; &#13; <p>I have been working on human rights violations in Turkey, particularly on torture and impunity, for over ten years. Turkey鈥檚 failure to account for the collective political violence in its history has been one of the main reasons which motivated me to pursue a PhD on this topic. Questioning approaches that establish a linear link between confession, truth and justice, I have sought to understand the workings of power in the confessional form of truth telling.</p>&#13; &#13; <p><strong>Day-to-day</strong></p>&#13; &#13; <p>I am currently in the final year of my PhD so I spend most of my time either at the library or at home writing my thesis. When I visit the department to meet my supervisor and fellow PhD students, I usually study at the 鈥楢ttic鈥, the study space provided for PhD students in the department. It provides quite an appealing atmosphere thanks to student initiatives including writing groups and coffee breaks. Due to my part-time job at the Human Rights Consortium, School of Advanced Study at 探花直播 of London, I also commute between London and Cambridge.<br />&#13; 聽<br /><strong>My best days聽</strong></p>&#13; &#13; <p>Cambridge is a unique place not only to indulge in solitary intellectual work but also to socialize with fellow academics in a wide range of events. As one of the conveners of the <a href="https://www.crassh.cam.ac.uk/research/projects-centres/performance-network">Cambridge Interdisciplinary Performance Network</a>, a research group at the <a href="https://www.crassh.cam.ac.uk/">Centre for Research in the Arts, Social Sciences and Humanities</a>, I also organise seminars on performance and performativity related themes. One of the seminars I recently organised featured Professor Leigh Payne from the 探花直播 of Oxford. It was a particularly special occasion for me as I decided to study聽confessions after I heard her talk at a workshop in Denmark.<br />&#13; 聽<br /><strong>I hope my work will lead to</strong>聽</p>&#13; &#13; <p>I want to contribute to the academic literature on political violence, truth and reconciliation, and thereby inform decision makers, scholars and broader public on some specific aspects of achieving and keeping peace by addressing the need for justice. More importantly, I hope my research will make people reflect on the roots of denial not only caused by forms of silencing but also by certain forms of speech.聽</p>&#13; &#13; <p>While I am planning to pursue an academic career, I would like to continue working in grassroots movements and NGOs on human rights violations. My future projects will involve both elements of research and art. Through interactive and creative projects, I aim to reflect upon alternative ways of working through the past.聽聽</p>&#13; &#13; <p><br /><strong>It had to be Cambridge because</strong></p>&#13; &#13; <p> 探花直播best part of studying at Cambridge has been its fulfilling and vibrant intellectual environment. In addition to the wide-ranging academic events featuring renowned scholars and research methods courses, I also had the chance to attend a short film making course which enhanced my digital story-telling skills. I have been very lucky to have an inspiring environment in the department thanks to the encouragement and support of my supervisor, <a href="https://research.sociology.cam.ac.uk/profile/professor-patrick-baert">Professor Patrick Baert</a>.</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>With our Postgraduate Open Day fast-approaching (3 November), we introduce five PhD students who are already making waves at Cambridge.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"> I&#039;m planning to pursue an academic career while continuing to work in grassroots movements and NGOs on human rights violations.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Yesim Yaprak Yildiz</div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Yesim Yaprak Yildiz</div></div></div><div class="field field-name-field-panel-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Postgraduate Open Day</div></div></div><div class="field field-name-field-panel-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information about the 探花直播's Postgraduate Open Day on 3rd November 2017 and to book to attend, <a href="https://www.postgraduate.study.cam.ac.uk/events">please click here</a>.</p>&#13; </div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 31 Oct 2017 11:07:45 +0000 ta385 192822 at Postgraduate Pioneers 2017 #2 /news/postgraduate-pioneers-2017-2 <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/news/sarahcropforweb_0.gif?itok=LFNPEWgN" alt="Sarah Harrison" title="Sarah Harrison, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div><strong>Second in the series is Sarah Harrison, a final year PhD student聽in the Department of Physiology, Development and Neuroscience, whose research highlights the importance of extra-embryonic cells and cell interactions.</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My research sets out to</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>My research tries pick apart what takes you from a single fertilized egg through to a body with head, tail and limbs and internal organs through embryonic development. And we mostly look at the mouse embryo to answer these questions and look at changes in cell shape, cell behavior and cell fate decisions along the way.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>Day-to-day</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>Rather than using whole mouse embryos to answer these questions about development, I derive stem cell populations from the embryos and maintain these in culture. What this means is that most of the time I鈥檓 standing in a small tissue culture room with my arms underneath a tissue culture hood to keep the cells happy and sterile. And then we grow the cells up and perform assays on how gene expression is changing when we change their culture conditions and try and plate them in scaffolds of 3D to generate embryo like structures. When I鈥檓 not in the culture room, I鈥檓 dissecting embryos, I鈥檓 down at the animals house looking after our transgenic mouse colonies and some of the time I鈥檓 sitting down doing data analysis. I鈥檓 in quite a <a href="https://mzglab.com/">collaborative group</a>,聽so it鈥檚 rare that it鈥檚 just one person working on one question. Actually we鈥檝e got lots of questions and we try to use all of our tools and expertise to answer them most effectively.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My best days</strong>聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>My favourite period in the lab was when I was just starting to put together the work that went on to get us a <a href="https://www.science.org/doi/10.1126/science.aal1810">first author publication</a>. That was when I was combining embryonic stem cells with stem cells that I鈥檇 derived from extra embryonic tissues, so tissues that would go on to form the placenta. Combining these two cell types in a dish started to generate, through self-organisational processes, structures that looked like embryos. And when I first saw this I couldn鈥檛 believe my eyes, it was amazing, and I couldn鈥檛 wait to tell my supervisor. And even though it was still quite early days, it showed that our hypothesis about interactions between embryonic and extra-embryonic cells being really important in generating a body, was working, so that was great.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>I hope my work will lead to</strong>聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I hope my PhD research will help the mouse embryology field at least to see the importance of cell interactions, and that it鈥檚 not just about the cells that go on to make the body but also the extra-embryonic cells that nourish the embryo. So hopefully it will provide a new slant on early embryology. For me personally, I feel I鈥檝e drilled right down into an incredibly precise area of life science. Now I鈥檇 like to broaden out a little bit and perhaps go into science publishing to be able to communicate these really interesting discoveries, many of which are happening right here in Cambridge.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>It had to be Cambridge because</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>In terms of developmental biology, there is nowhere like Cambridge. <a href="https://www.pdn.cam.ac.uk/"> 探花直播building I鈥檓 in now聽is where scientists pioneered IVF</a>, for instance. So that history is a major factor for people, but it鈥檚 not just about past breakthroughs, it鈥檚 about what鈥檚 going on now. I can go across the road to another building and chat to someone who is developing ways to encapsulate cells in tiny beads of gel, and really high tech, high through-put methods are being developed all around. And so it鈥檚 a great place to develop your research, not just in the techniques you know and love, but to expand and be more collaborative. On top of that, socially it鈥檚 great. We can go to lots of different institutes, and develop not just professional collaborations but also social collaborations, where we share ideas and results to get feedback. Having all these clever people around is a big benefit for developing.</div>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>With our Postgraduate Open Day fast-approaching (3 Nov), we introduce five PhD candidates who are already making waves at Cambridge.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"> I couldn鈥檛 believe my eyes, it was amazing, and I couldn鈥檛 wait to tell my supervisor.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Sarah Harrison, final year PhD student</div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Sarah Harrison</div></div></div><div class="field field-name-field-panel-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Postgraduate Open Day</div></div></div><div class="field field-name-field-panel-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><div>For more information about the 探花直播's Postgraduate Open Day on 3rd November 2017 and to book to attend, <a href="https://www.postgraduate.study.cam.ac.uk/events">please click here</a>.</div>&#13; </div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width: 0px;" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Wed, 25 Oct 2017 12:39:35 +0000 ta385 192602 at Postgraduate Pioneers 2017 #1 /news/postgraduate-pioneers-2017-1 <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/news/himanshabestforweb.gif?itok=5GEbkaAL" alt="Himansha Singh, Dept of Pharmacology" title="Himansha Singh, Dept of Pharmacology, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div><strong>First in the series is聽Himansha聽Singh, a Pharmacologist from India whose research aims to help tackle antimicrobial resistance.</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My research sets out to</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>Today, we can survive an organ transplant but then die because of a bacterial infection. 探花直播rise of antimicrobial resistance (AMR) and 鈥榮uperbugs鈥, along with the lack of antibiotic development in the last decades, is a major concern for global healthcare. Whilst there are several mechanisms responsible for AMR, our research group is examining multidrug efflux pumps or transporters that expel drugs rendering bacteria resistant to a broad range of antibiotics.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>While we know some things about the architecture of bacteria, we don鈥檛 fully understand how they conduct transportation of antibiotics. If we could understand their operating system, we could develop compounds, which might help switching off the system and stop them from rejecting antibiotics. In particular, my project is looking into a very interesting <a href="https://www.nature.com/articles/ncomms12387">E.coli ATP-binding cassette (ABC) transporter MsbA</a>. We are working towards characterising how this protein uses energy to operate dynamic changes in its structure to facilitate drug transport.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My Motivation</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>During my master's degree, I worked with AstraZeneca and my neighbouring lab was working on transporters in drug development. Their work caught my attention. I also visited India that summer and my hometown, Gwalior, in Madhya Pradesh, was suffering a severe outbreak of tuberculosis and typhoid. These experiences exposed me to the seriousness of antibiotic resistance. Transporters play a huge role in this and after reading up on the topic, I looked for a relevant PhD project and was delighted to be accepted into <a href="https://www.phar.cam.ac.uk/research/vanveen">Dr Hendrik W. van Veen's</a> lab to work on various transporters, both in humans and bacteria.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>Day-to-day</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>I am based in the <a href="https://www.phar.cam.ac.uk/">Department of Pharmacology</a>, which is in the city center 鈥 it鈥檚 a great location. I work in a team of ten and my average day in the lab is spent working on culturing liters of bacterial cells to extract MsbA and reconstitute it in artificial lipid membranes. I then test MsbA activity under different energy conditions and drugs, or test different inhibitors.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>My best days</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>That has to be when we first noticed that the ATP dependent transporter MsbA could also work without ATP. ATP is an energy currency of cells and ABC transporters, such as MsbA, utilize it as their main source of power for drug transport. But we showed that MsbA is also dependent on another form of energy source, an electrochemical gradient. In fact, MsbA cannot function without the involvement of both of these power sources. That brought a paradigm shift in our understanding of translocation by MsbA, which may lead us to new ways to tackle bacteria.</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>I hope my work will lead to聽</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>Apart from being a multidrug transporter, MsbA is an essential membrane protein that transports phospholipids in E.coli to form its cell membrane; so inhibiting this pump is clinically important to develop or establish foundations for a new class of antibiotics against E.coli. We can only design inhibitors if we know the fundamental basis of their transport mechanism and I hope my PhD research will provide some insight into this.聽 We believe that our findings will be of great interest to the wider scientific community.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div><strong>It had to be Cambridge because</strong></div>&#13; &#13; <div>聽</div>&#13; &#13; <div>My supervisor,聽<a href="https://www.phar.cam.ac.uk/research/vanveen">Dr.聽Hendrik聽W. van聽Veen</a> has played a crucial role in developing my enthusiasm for scientific research. And Cambridge has provided a tight-knit, supportive and stimulating intellectual environment which has shaped my career and understanding of academia in really important ways. Other than benefiting from the world-class research facilities in my lab and department, I鈥檝e been able to immerse myself in Cambridge鈥檚 rich culture and exciting critical atmosphere. 探花直播collegiate system also ensures a thriving social life and this paved the way for me to develop interests in various other disciplines over formal dinners and drinks in our college bars.聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>聽</div>&#13; &#13; <div>&#13; <div><strong>In 2017, Himansha聽Singh was one of twelve PhD students to win an award from the <a href="http://www.csar.org.uk/student-awards/2017/">Cambridge Society for the Application of Research</a>.</strong></div>&#13; </div>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>With our Postgraduate Open Day fast approaching (3 Nov), we introduce five PhD students聽who are already making waves at Cambridge.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">I have benefited from world-class research facilities and immersed myself in Cambridge鈥檚 rich culture. </div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Himansha Singh</div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Himansha Singh, Dept of Pharmacology</div></div></div><div class="field field-name-field-panel-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Postgraduate Open Day</div></div></div><div class="field field-name-field-panel-body field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information about the 探花直播's Postgraduate Open Day on 3rd November 2017 and to book to attend, <a href="https://www.postgraduate.study.cam.ac.uk/events">please click here</a>.</p>&#13; </div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; 探花直播text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>. For image use please see separate credits above.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 17 Oct 2017 10:00:00 +0000 ta385 192292 at