ֱ̽ of Cambridge - ֱ̽ of Reading /taxonomy/external-affiliations/university-of-reading en Road radar to reveal York's Roman secrets /research/news/road-radar-to-reveal-yorks-roman-secrets <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/york590x288.jpg?itok=iY4n2GBa" alt="View of the city of York in England including walls and cathedral" title="View of the city of York in England including walls and cathedral, Credit: None" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>Did the Romans alter their legionary fortress at Eboracum in the late Antique period? What was the settlement around it like and how did this change? Did Eboracum receive a makeover when emperors came to town?</p>&#13; &#13; <p>These are just some of the questions which Cambridge archaeologist Professor Martin Millett and his colleagues hope to answer without lifting a single spade or trowel.</p>&#13; &#13; <p>Over summer 2022, a vehicle equipped with specialist radar equipment will survey 20km of streets around York – the first time a project on this scale has been undertaken in the UK. ֱ̽team behind the scheme are working with City of York Council to access as much of the city centre road network as possible, including some pedestrianised streets, during the survey, with minimal disruption to the public.</p>&#13; &#13; <p>Alongside the road surveys, a different radar system will scan the green spaces in the city centre, particularly around the Yorkshire Museum and York Minster.</p>&#13; &#13; <p> ֱ̽initiative is a joint project between Universities of Cambridge and Reading, York Archaeology and the York Museums Trust funded by the Arts &amp; Humanities Research Council (AHRC). ֱ̽30-month-long project aims to collate everything archaeologists and historians know about the whole of Roman York into a single database which will then be made freely available to the public.</p>&#13; &#13; <p>Among many other things, the team will be looking for evidence of Eboracum's architecture and infrastructure being enhanced during periods of imperial residence (AD 208–11 and AD 305-06), or following York’s promotion to colonial status in the early 3rd century. They are also hoping to find evidence for changes in the organization and use of land in the immediate environs of York through the Roman period.</p>&#13; &#13; <p>Alongside the research there will be a series of public engagement projects including volunteer-run research projects, an art initiative and a project for schools around the country linking research findings to geography, physics, geology and archaeology.</p>&#13; &#13; <p> ֱ̽radar mapping exercise will start in the summer, with dry weather being crucial to the success of the scanning, as the radar can only penetrate down to the water table, which is notoriously high for much of the year in York.</p>&#13; &#13; <p>Project leader Martin Millett, Laurence Professor of Classical Archaeology at Cambridge and a trustee of York Archaeological Trust, said: “This is a key initiative where we hope to learn much more about the layout of the Roman city without having to dig a single trench.”</p>&#13; &#13; <p>Co-investigator Dr John Creighton of the ֱ̽ of Reading said: “Over many years, various investigations have opened small windows into different parts of the Roman city, but we hope that this scanning will reveal far more about the city including details where the roads and significant buildings in the city were located, particularly around Micklegate.”</p>&#13; &#13; <p> ֱ̽wider research will bring together not only the results of archaeological excavations over the last 50 years, but also other less formal sources of information, including historic press reports of Roman finds, notebooks and published reports from the 18th century onwards. It is hoped that volunteers from across the community will be involved.</p>&#13; &#13; <p>Cllr Darryl Smalley, Executive Member for Culture, Leisure and Communities at City of York Council, said: “This exciting new project will provide a new basis for understanding of Roman York and will enhance the ways in which the City can assess the impact of planning and future development on this valuable but hidden heritage.”</p>&#13; &#13; <p>Updates on the project will be posted on <a href="https://www.yorkarchaeology.co.uk/romanyork">yorkarchaeology.co.uk/romanyork</a></p>&#13; &#13; <p>Professor Millett recently led the team which successfully mapped a complete Roman city, Falerii Novi, in Italy, using the same technology. This research received global media coverage. <a href="/stories/roman-city-rises">Find out more here</a>.</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p> ֱ̽biggest investigation ever undertaken into Eboracum, the Roman city buried beneath York, is set to begin this summer. Ground penetrating radar will be used to map as much of the influential ancient settlement as possible in a bid to learn more about its evolving layout and use.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">We hope to learn much more about the layout of the Roman city</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Martin Millett</div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">View of the city of York in England including walls and cathedral</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img alt="Creative Commons License" src="https://i.creativecommons.org/l/by/4.0/88x31.png" style="border-width:0" /></a><br />&#13; ֱ̽text in this work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>. Images, including our videos, are Copyright © ֱ̽ of Cambridge and licensors/contributors as identified.  All rights reserved. We make our image and video content available in a number of ways – as here, on our <a href="/">main website</a> under its <a href="/about-this-site/terms-and-conditions">Terms and conditions</a>, and on a <a href="/about-this-site/connect-with-us">range of channels including social media</a> that permit your use and sharing of our content under their respective Terms.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 01 Mar 2022 08:00:00 +0000 ta385 230241 at Pollinators: first global risk index for species declines and effects on humanity /stories/pollinatorsriskindex <div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p> ֱ̽Global South may have most to lose from pollinator loss, with Latin America at particular risk due to crop exports and indigenous cultures.</p> </p></div></div></div> Mon, 16 Aug 2021 15:01:29 +0000 fpjl2 225981 at Plant scientists call for rethink of GM crop regulation /research/news/plant-scientists-call-for-rethink-of-gm-crop-regulation <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/140319-field-gm.jpg?itok=508IoM_6" alt="Field and sky" title="Field and sky, Credit: Jesper Dyhre Nielsen" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>In a report to the Council for Science and Technology, which advises the Prime Minister on science policy, the scientists warn that unless GM crops are regulated at national, rather than at EU level, European agriculture could suffer because it will be unable to adopt GM crops.</p>&#13; &#13; <p> ֱ̽new regulatory system should be modelled on the way pharmaceuticals are licensed in the UK, says the report, which was written by scientists at the universities of Cambridge and Reading, ֱ̽Sainsbury Laboratory and Rothamsted Research.</p>&#13; &#13; <p>According to lead author Professor Sir David Baulcombe of the Department of Plant Sciences at Cambridge: “Most concerns about GM crops have nothing to do with the technology, which is as safe as conventional breeding.</p>&#13; &#13; <p>“They are more often related to the way that the technology is applied and whether it is beneficial for small scale farmers or for the environment. To address these concerns we need to have an evidence-based regulatory process that focuses on traits, independent of the technology that has been used to develop them.”</p>&#13; &#13; <p>This is the approach used for regulating pharmaceuticals, regulators looking at the effects that new drugs have on patients, not at the technology used to develop them – which in many cases involves genetic modification.</p>&#13; &#13; <p> ֱ̽<a href="https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/292174/cst-14-634a-gm-science-update.pdf">report</a> recommends the European Food Safety Authority retains an advisory role on risk and safety, similar to the European Medicines Agency for pharmaceuticals, but that approval is made on a national basis, as by the National Institute for Clinical Excellence in the UK.</p>&#13; &#13; <p>“As there is no evidence for intrinsic environmental or toxicity risks associated with GM crops, it is not appropriate to have a regulatory framework that is based on the premise that GM crops are more hazardous than crop varieties produced by conventional plant breeding,” it says.</p>&#13; &#13; <p>Since GM crops were first developed 30 years ago, major advances in basic science have led to new methods for transferring genes into specific locations in a crop plant's genome.</p>&#13; &#13; <p>To respond to today's challenges of population growth, climate change and environmental degradation, as well as the need to develop biofuels and other materials, the report argues plant breeders in the UK – which is a world leader in plant genomics – need GM technology and a well-functioning R&amp;D pipeline for both GM and non-GM crop varieties.</p>&#13; &#13; <p>GM crops were first grown commercially in the USA in 1994, and in Europe in 1998. They are now grown in 28 countries worldwide, with GM crops currently accounting for 12% of global arable acreage. Most of that acreage is soybean and cotton, and 81% of the global acreage of these crops is sown to GM varieties.</p>&#13; &#13; <p>However, even though 70% of protein fed to livestock in the European Union is imported as GM crop products, less than 0.1% of the global acreage of GM crops is cultivated in Europe. This, the report argues, is because experimentation and commercial release of GM crops in the EU is subject to much more stringent regulation than conventionally bred plants, with a slow and inefficient approval process.</p>&#13; &#13; <p>As a result, multinational companies such as BASF and Monsanto have abandoned research to develop GM crops in Europe, and there has been a significant reduction in experimental field trials in the UK, with only one in 2012, compared with 37 in 1995.</p>&#13; &#13; <p>To ensure a well-functioning research and development pipeline that can translate genomic research from the laboratory to the market place, the report also recommends establishing a new R&amp;D capacity – PubGM.</p>&#13; &#13; <p>PubGM would allow preliminary evaluation of the practical application of academic research findings to crops, including field testing new GM crops either in partnership with companies or so that the public sector could validate traits before engaging in partnerships with the private sector.</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Leading plant scientists have called for major changes to the way GM crops are licensed.</p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">Most concerns about GM crops have nothing to do with the technology, which is as safe as conventional breeding.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Professor Sir David Baulcombe</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/" target="_blank">Jesper Dyhre Nielsen</a></div></div></div><div class="field field-name-field-image-desctiprion field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Field and sky</div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by-nc-sa/3.0/"><img alt="" src="/sites/www.cam.ac.uk/files/80x15.png" style="width: 80px; height: 15px;" /></a></p>&#13; &#13; <p>This work is licensed under a <a href="http://creativecommons.org/licenses/by-nc-sa/3.0/">Creative Commons Licence</a>. If you use this content on your site please link back to this page.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div><div class="field field-name-field-license-type field-type-taxonomy-term-reference field-label-above"><div class="field-label">Licence type:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/taxonomy/imagecredit/attribution-noncommercial-sharealike">Attribution-Noncommercial-ShareAlike</a></div></div></div> Wed, 19 Mar 2014 11:50:22 +0000 jfp40 123182 at Study confirms a gene linked to Asperger Syndrome and empathy /research/news/study-confirms-a-gene-linked-to-asperger-syndrome-and-empathy <div class="field field-name-field-news-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img class="cam-scale-with-grid" src="/sites/default/files/styles/content-580x288/public/news/research/news/puzzle.jpg?itok=PAjNX2ZG" alt="" title="Credit: John Hritz" /></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p>A study published this month in the journal <a href="https://molecularautism.biomedcentral.com/articles/10.1186/2040-2392-4-48"><em>Molecular Autism</em></a> confirms previous research that people with Asperger Syndrome (AS) are more likely to carry specific variations in a particular gene. More strikingly, the study supports existing findings that the same gene is also linked to how much empathy typically shown by individuals in the general population.</p>&#13; &#13; <p> ֱ̽research was carried out by a team of researchers led by Professor Baron-Cohen at the Autism Research Centre at Cambridge ֱ̽. Asperger Syndrome is an autism spectrum condition. ֱ̽researchers looked for sequence variations (called single nucleotide polymorphisms or SNPs) in the gene known as GABRB3 in a total of 530 adults - 118 people diagnosed with AS and 412 people without a diagnosis.</p>&#13; &#13; <p> ֱ̽team found that certain SNPs in GABRB3 were significantly more common in people with AS. They also discovered that additional genetic variations in the same gene were linked to scores on an empathy measure called the Empathy Quotient (EQ) in the general population.</p>&#13; &#13; <p>AS is diagnosed when a person struggles with social relationships and communication, and shows unusually narrow interests and resistance to change, but has good intelligence and language skills. Most genetic studies of autistic spectrum conditions treat autism as if they are all very similar, whereas in reality there is considerable variation (e.g., in language level and intellectual ability).</p>&#13; &#13; <p>Rather than studying people on the autistic condition spectrum, this new study looked only people with AS, as a well-defined subgroup of individuals within this range.  ֱ̽researchers examined the gene GABRB3 which regulates the functioning of a neurotransmitter called gamma-aminobutyric acid (GABA) and which contains a number of SNPs that vary across the population.</p>&#13; &#13; <p> ֱ̽volunteers were tested for 45 SNPs within this key gene. ֱ̽team had previously found that SNPs in this gene were more common in adults with AS and also showed a relationship with empathy levels and tactile sensitivity (how sensitive people are to being touched) in the general population.</p>&#13; &#13; <p>Testing a new sample of volunteers who had not taken part in previous studies, the researchers found that three of the SNPs were again more common in adults with AS, and two different SNPs in the same gene were again related to empathy levels in the general population, confirming that the gene is involved in autism spectrum conditions.</p>&#13; &#13; <p>Professor Baron-Cohen said: “We are excited that this study confirms that variation in GABRB3 is linked not just to AS but to individual differences in empathy in the population. Many candidate genes do not replicate across studies and across different samples, but this genetic finding seems to be a solid result. Research now needs to focus on where this gene is expressed in the brain in autism, and how it interacts with other genetic and non-genetic factors that cause AS.”</p>&#13; &#13; <p> ֱ̽team was co-led by Dr Bhismadev Chakrabarti from the Department of Psychology at Reading ֱ̽. He commented: “Genes play an important role in autism and Asperger Syndrome. This new study adds to evidence that GABRB3 is a key gene underlying these conditions. This gene is involved in the functioning of a neurotransmitter that regulates excitation and inhibition of nerve cell activity so the research gives us vital additional information about how the brain may develop differently in people with Asperger Syndrome.”</p>&#13; &#13; <p>Varun Warrier, who carried out the study as part of his graduate research at Cambridge ֱ̽, added: “ ֱ̽most important aspect of this research is that it points to common genetic variants in GABRB3 being involved in both AS and in empathy as a dimensional trait. Although GABRB3 is not the only gene to be involved in this condition and in empathy levels, we are confident that we have identified one of the key players. We are following this up by testing how much protein GABRB3 produces in the brain in autism, since a genetic finding of this kind becomes more explanatory when we can also measure its function.”</p>&#13; </div></div></div><div class="field field-name-field-content-summary field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><p><p>Scientists have confirmed that variations in a particular gene play a key role in the autism spectrum condition known as Asperger Syndrome. They have also found that variations in the same gene are also linked to differences in empathy levels in the general population. </p>&#13; </p></div></div></div><div class="field field-name-field-content-quote field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even">This study confirms that variation in GABRB3 is linked not just to Asperger Syndrome but to individual differences in empathy in the population.</div></div></div><div class="field field-name-field-content-quote-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Simon Baron-Cohen</div></div></div><div class="field field-name-field-image-credit field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.flickr.com/photos/29818924@N00/409083204/in/photolist-C9EbG-DmMVY-JSVeX-PaQu3-RrQ1E-2MTaho-2UUGno-36YrR2-3bboEr-3cBdtd-3ekzr5-49eBa7-4aj6wU-4eMTQm-4fpHk2-4m28Z8-4q6yU4-4qaFj3-4r5tZ8-4riVxc-4rAM9f-58BJWE-59cK4X-59BFCr-5g2tSn-5g6PTY-5g6Qed-5oj57V-5sr428-5vWtga-5woxh8-5zQF6x-5JTESj-5K6JER-5KXvJc-5MX9iS-5S6Whs-5S6Whu-5SfK7D-5T78KJ-6chUJv-6r4zBu-6sYKTc-6NCGPm-77RyN3-7k44Xv-7oVHFt-7vMp9N-bzkEFh-7EVYj8-aSj57v" target="_blank">John Hritz</a></div></div></div><div class="field field-name-field-cc-attribute-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><a href="http://creativecommons.org/licenses/by-nc-sa/3.0/"><img alt="" src="/sites/www.cam.ac.uk/files/80x15.png" style="width: 80px; height: 15px;" /></a></p>&#13; &#13; <p>This work is licensed under a <a href="http://creativecommons.org/licenses/by-nc-sa/3.0/">Creative Commons Licence</a>. If you use this content on your site please link back to this page.</p>&#13; </div></div></div><div class="field field-name-field-show-cc-text field-type-list-boolean field-label-hidden"><div class="field-items"><div class="field-item even">Yes</div></div></div> Tue, 17 Dec 2013 08:00:00 +0000 amb206 111062 at