̽��ֱ�� of Cambridge - Cambridgeshire and Peterborough NHS Foundation Trust

Cambridge joins forces with ARIA to fast-track radical new technologies to revolutionise brain health

Anonymous — Wed, 09 Oct 2024 12:57:22 +0000

̽��ֱ��collaboration, which includes researchers from the ̽��ֱ�� of Cambridge, aims to accelerate progress on new neuro-technologies, including miniaturised brain implants designed to treat depression, dementia, chronic pain, epilepsy and injuries to the nervous system.

Neurological and mental health disorders will affect four in every five people in their lifetimes, and present a greater overall health burden than cancer and cardiovascular disease combined. For example, 28 million people in the UK are living with chronic pain and 1.3 million people with traumatic brain injury.

Neuro-technology – where technology is used to control the nervous system - has the potential to deliver new treatments for these disorders, in much the same way that heart pacemakers, cochlear implants and spinal implants have transformed medicine in recent decades.

̽��ֱ��technology can be in the form of electronic brain implants that reset abnormal brain activity or help deliver targeted drugs more effectively, brain-computer interfaces that control prosthetic limbs, or technologies that train the patient’s own cells to fight disease. ARIA’s Scalable Neural Interfaces opportunity space is exploring ways to make the technology more precise, less invasive, and applicable to a broader range of diseases.

Currently, an implant can only interact with large groups of neurons, the cells that transmit information around the brain. Building devices that interact with single neurons will mean a more accurate treatment. Neuro-technologies also have the potential to treat autoimmune disorders, including rheumatoid arthritis, Crohn’s disease and type-1 diabetes.

̽��ֱ��science of building technology small enough, precise enough and cheap enough to make a global impact requires an environment where the best minds from across the UK can collaborate, dream up radical, risky ideas and test them without fear of failure.

Professor George Malliaras from the ̽��ֱ�� of Cambridge’s Department of Engineering is one of the project leaders. “Miniaturised devices have the potential to change the lives of millions of people currently suffering from neurological conditions and diseases where drugs have no effect,” he said. “But we are working at the very edge of what is possible in medicine, and it is hard to find the support and funding to try radical, new things. That is why the partnership with ARIA is so exhilarating, because it is giving brilliant people the tools to turn their original ideas into commercially viable devices that are cheap enough to have a global impact.”

Cambridge’s partnership with ARIA will create a home for original thinkers who are struggling to find the funding, space and mentoring needed to stress-test their radical ideas. ̽��ֱ��three-year partnership is made up of two programmes:

̽��ֱ��Fellowship Programme (up to 18 fellowships)

Blue Sky Fellows – a UK-wide offer - we will search the UK for people from any background, with a radical idea in this field and the plan and personal skills to develop it. ̽��ֱ��best people will be offered a fellowship with the funding to test their ideas in Cambridge rapidly. These Blue Sky Fellows will receive mentorship from our best medical, scientific and business experts and potentially be offered accommodation at a Cambridge college. We will be looking for a specific type of person to be a Blue Sky Fellow. They must be the kind of character who thinks at the very edge of the possible, who doesn’t fear failure, and whose ideas have the potential to change billions of lives, yet would struggle to find funding from existing sources. Not people who think outside the box, more people who don’t see a box at all.

Activator Fellows - a UK-wide offer - those who have already proved that their idea can work, yet need support to turn it into a business, will be invited to become Activator Fellows. They will be offered training in entrepreneurial skills including grant writing, IP management and clinical validation, so their innovation can be ready for investment.

̽��ֱ��Ecosystem Programme

̽��ֱ��Ecosystem Programme is about creating a vibrant, UK-wide neurotechnology community where leaders from business, science, engineering, academia and the NHS can meet, spark ideas and form collaborations. This will involve quarterly events in Cambridge, road trip events across the UK and access to the thriving online Cambridge network, Connect: Health Tech.

“This unique partnership is all about turning radical ideas into practical, low-cost solutions that change lives,” said Kristin-Anne Rutter, Executive Director of Cambridge ̽��ֱ�� Health Partners. “Cambridge is fielding its best team to make this work and using its networks to bring in the best people from all over the UK. From brilliant scientists to world-leading institutes, hospitals and business experts, everyone in this collaboration is committed to the ARIA partnership because, by working together, we all see an unprecedented opportunity to make a real difference in the world.”

“Physical and mental illnesses and diseases that affect the brain such as dementia are some of the biggest challenges we face both as individuals and as a society,” said Dr Ben Underwood, Associate Professor of Psychiatry at the ̽��ֱ�� of Cambridge and Honorary Consultant Psychiatrist at Cambridgeshire and Peterborough NHS Foundation Trust. “This funding will bring together different experts doing things at the very limits of science and developing new technology to improve healthcare. We hope this new partnership with the NHS will lead to better care and treatment for people experiencing health conditions.”

Cambridge partners in the project include the Departments of Engineering and Psychiatry, Cambridge Neuroscience, the Milner Therapeutics Institute, the Maxwell Centre, Cambridge ̽��ֱ�� Health Partners (CUHP), Cambridge Network, the Babraham Research Campus, Cambridgeshire and Peterborough NHS Foundation Trust, and Vellos.

A team from across the Cambridge life sciences, technology and business worlds has announced a multi-million-pound, three-year collaboration with the Advanced Research and Invention Agency (ARIA), the UK government’s new research funding agency.

Science Photo Library via Getty Images

Illustration of human brain

̽��ֱ��text in this work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Images, including our videos, are Copyright © ̽��ֱ�� of Cambridge and licensors/contributors as identified. All rights reserved. We make our image and video content available in a number of ways – on our main website under its Terms and conditions, and on a range of channels including social media that permit your use and sharing of our content under their respective Terms.

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New milestone for specialist children’s hospital in the East of England

ta385 — Thu, 12 Oct 2023 10:00:16 +0000

̽��ֱ��Project had its Outline Business Case approved in principle by NHS England and the Department of Health and Social Care on 29 September 2023. With this approval, which is subject to a review of the Project’s capital funding in April 2024, work can now commence on the Full Business Case for the Project.

̽��ֱ��hospital, which was awarded planning permission in March 2022, is being built on the Cambridge Biomedical Campus, but will care for children and young people across the whole of Norfolk, Suffolk, Essex, Hertfordshire, Bedfordshire and Cambridgeshire.

It will be the first hospital designed to truly provide mental and physical health care together, delivered by staff who are trained in both. While the hospital will be built in Cambridge it will act as a central hub, working with services all over the East of England to provide care and support for children who may never visit the hospital itself.

Dr Rob Heuschkel, Cambridge Children’s Hospital Clinical Lead for Physical Health said: “This is fantastic news for children across the East of England – the only region without a specialist children’s hospital.

“We know there is widespread support across the East of England for this Hospital – from children and their families to our regional colleagues and our regional MPs. Now is the time for us to all work together to turn our plans into reality. I can’t wait to get started on the next stage of this Project. “

̽��ֱ��government committed £100m to Cambridge Children’s Hospital in 2018, under the Sustainability and Transformation Partnership scheme, and the project is on track to meet its target of an additional £100m of philanthropy and fundraising.

Health Minister Lord Markham said: “We are investing in over 70 major new upgrades of NHS facilities across the country so patients can access high quality care in state-of-the-art hospitals, both now and in the years to come. I’m pleased Cambridge Children’s Hospital is now starting on the final stage of its business case with construction planned to begin next year.

“Backed by £100 million of government funding, this hospital will be the first specialist children’s hospital for the East of England and will bring mental and physical healthcare services together to benefit thousands of young people.”

Dr Cathy Walsh, Cambridge Children’s Hospital Clinical Lead for Mental Health, said: “There’s a long way still to go but this is an exciting moment in our journey to building a truly integrated children’s hospital.

“Our young people urgently need a new type of care, delivered by staff who are trained in both mental and physical health care. Cambridge Children’s Hospital will completely transform the future of healthcare for children and their families from across this region.”

̽��ֱ��hospital will also house a ̽��ֱ�� of Cambridge world-class research facility focussed on detecting and preventing childhood illness.

Professor David Rowitch, Head of the Department of Paediatrics at the ̽��ֱ�� of Cambridge and Cambridge Children’s Hospital Research Lead, said: “Cambridge Children’s Hospital will use cutting-edge innovations in genomic science to detect origins of physical and mental health conditions and develop a new model of preventive medicine in paediatrics. We will foster game-changing breakthroughs in life sciences research that will have an impact across the globe.

“Together we can detect childhood disease early or prevent it altogether, personalise health care and deliver it closer to home.”

Members of Cambridge Children’s Hospital Network, which is made up of children, young people and parents from across the region, have been a crucial part of designing the future hospital, and helping to shape how the facility might look and feel like.

Sarah Cobb, 19 from near Cambridge, has multiple disabilities and is visually impaired. She has been involved in the Project for a number of years. She said: “As someone with lifelong health conditions, who’s spent a lot of time in hospital as a child, a teenager and now a young adult, I’m delighted that Cambridge Children’s Hospital has reached this brilliant milestone.

“I feel really honoured to be part of such an inspirational project. This hospital means so much to me and will make such a difference to the mental and physical health of children and young people in future.”

Work continues on finalising the costs and remaining funding streams for this brand new hospital. We will now start developing the final stage of the business case for Cambridge Children’s Hospital’s– the Full Business Case.

Cambridge Children’s Hospital, which will be the first specialist children’s hospital for the East of England, has been given the green light to proceed to the final stage of its business case development. This means that pre-construction works can begin on the site of the new hospital, opposite the Rosie Maternity Hospital on Robinson Way, early next year.

Together we can detect childhood disease early or prevent it altogether, personalise health care and deliver it closer to home

David Rowitch

Artist's impression of the entrance to the future Cambridge Children’s Hospital

About Cambridge Children’s Hospital

Cambridge Children’s Hospital will be the first hospital designed to truly provide mental and physical health care together, delivered by staff who are trained in both.

It is the first specialist children’s hospital for the East of England, the only region in the UK without one.

̽��ֱ��hospital will fully integrate physical and mental healthcare services under one roof to provide a whole new way of caring for children and young people aged 0-19, including those with cancer.

Cambridge Children’s Hospital will be a national exemplar. Housing ̽��ֱ�� of Cambridge research institutes focused on the prevention and early diagnosis of disease, the hospital will deliver game-changing advances in life sciences research.

̽��ֱ��hospital will be built on Europe’s leading life sciences campus, the Cambridge Biomedical Campus, and is being co-designed with the help of young people, families and healthcare professionals.

Established by Cambridge ̽��ֱ�� Hospitals NHS Foundation Trust, Cambridgeshire and Peterborough NHS Foundation Trust and the ̽��ֱ�� of Cambridge, the hospital is a partnership which brings together clinical expertise and world-leading knowledge.

̽��ֱ��Campaign for Cambridge Children’s Hospital, a partnership between Addenbrooke’s Charitable Trust (ACT), Head to Toe Charity and the ̽��ֱ�� of Cambridge (CUDAR), is committed to raising £100 million from philanthropy and fundraising.

̽��ֱ��text in this work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Images, including our videos, are Copyright © ̽��ֱ�� of Cambridge and licensors/contributors as identified. All rights reserved. We make our image and video content available in a number of ways – as here, on our main website under its Terms and conditions, and on a range of channels including social media that permit your use and sharing of our content under their respective Terms.

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Ukrainian students depart

Anonymous — Fri, 16 Sep 2022 16:22:11 +0000

̽��ֱ��Ukrainian medical students who received essential training at Cambridge ̽��ֱ�� over the summer will take the specialist skills they have learned back home following a 7-week programme of clinical placements.

Ukrainian medical students arrive at Cambridge ̽��ֱ�� for vital clinical placements

sb726 — Fri, 05 Aug 2022 03:30:27 +0000

̽��ֱ�� of Cambridge is partnering with Kharkiv National Medical ̽��ֱ�� to provide expert teaching and support the Ukrainian health and education systems.

Mindfulness can improve mental health and wellbeing – but unlikely to work for everyone

cjb250 — Mon, 11 Jan 2021 19:00:26 +0000

Mindfulness is typically defined as ‘the awareness that emerges through paying attention on purpose, in the present moment, and nonjudgmentally to the unfolding of experience moment by moment’. It has become increasingly popular in recent years as a way of increasing wellbeing and reducing stress levels.

In the UK, the National Health Service offers therapies based on mindfulness to help treat mental health issues such as depression and suicidal thoughts. However, the majority of people who practice mindfulness learn their skills in community settings such as universities, workplaces, or private courses. Mindfulness-based programmes are frequently promoted as the go-to universal tool to reduce stress and increase wellbeing, accessible to anyone, anywhere.

Many randomised controlled trials (RCTs) have been conducted around the world to assess whether in-person mindfulness training can improve mental health and wellbeing, but the results are often varied. In a report published today in PLOS Medicine, a team of researchers from the Department of Psychiatry at the ̽��ֱ�� of Cambridge led a systematic review and meta-analysis to examine the published data from the RCTs. This approach allows them to bring together existing – and often contradictory or under-powered – studies to provide more robust conclusions.

̽��ֱ��team identified 136 RCTs on mindfulness training for mental health promotion in community settings. These trials included 11,605 participants aged 18 to 73 years from 29 countries, more than three-quarters (77%) of whom were women.

̽��ֱ��researchers found that in most community settings, compared with doing nothing, mindfulness reduces anxiety, depression and stress, and increases wellbeing. However, the data suggested that in more than one in 20 trials settings, mindfulness-based programmes may not improve these outcomes.

Dr Julieta Galante from the Department of Psychiatry at the ̽��ֱ�� of Cambridge, the report’s first author, said: “For the average person and setting, practising mindfulness appears to be better than doing nothing for improving our mental health, particularly when it comes to depression, anxiety and psychological distress – but we shouldn’t assume that it works for everyone, everywhere.

“Mindfulness training in the community needs to be implemented with care. Community mindfulness courses should be just one option among others, and the range of effects should be researched as courses are implemented in new settings. ̽��ֱ��courses that work best may be those aimed at people who are most stressed or in stressful situations, for example health workers, as they appear to see the biggest benefit.”

̽��ֱ��researchers caution that RCTs in this field tended to be of poor quality, so the combined results may not represent the true effects. For example, many participants stopped attending mindfulness courses and were not asked why, so they are not represented in the results. When the researchers repeated the analyses including only the higher quality studies, mindfulness only showed effects on stress, not on wellbeing, depression or anxiety.

When compared against other ‘feel good’ practices such as exercise, mindfulness fared neither better nor worse. Professor Peter Jones, also from Cambridge’s Department of Psychiatry, and senior author, said: “While mindfulness is often better than taking no action, we found that there may be other effective ways of improving our mental health and wellbeing, such as exercise. In many cases, these may prove to be more suitable alternatives if they are more effective, culturally more acceptable or are more feasible or cost effective to implement. ̽��ֱ��good news is that there are now more options.”

̽��ֱ��researchers say that the variability in the success of different mindfulness-based programmes identified among the RCTs may be down to a number of reasons, including how, where and by whom they are implemented as well as at whom they are targeted. ̽��ֱ��techniques and frameworks taught in mindfulness have rich and diverse backgrounds, from early Buddhist psychology and meditation through to cognitive neuroscience and participatory medicine – the interplay between all of these different factors can be expected to influence how effective a programme is.

̽��ֱ��number of online mindfulness courses has increased rapidly, accelerated further by the COVID-19 pandemic. Although this review has not looked at online courses, studies suggest that these may be as effective as their offline counterparts, despite most lacking interactions with teacher and peers.

Dr Galante added: “If the effects of online mindfulness courses vary as widely according to the setting as their offline counterparts, then the lack of human support they offer could cause potential problems. We need more research before we can be confident about their effectiveness and safety.”

̽��ֱ��research was mainly funded by the National Institute for Health Research.

Reference
Galante, J et al. Mindfulness-based programmes for mental health promotion in adults in non-clinical settings: A systematic review and meta-analysis of randomised controlled trials. PLOS Medicine; 11 Jan 2021; DOI: 10.1371/journal.pmed.1003481

Mindfulness courses can reduce anxiety, depression and stress and increase mental wellbeing within most but not all non-clinical settings, say a team of researchers at the ̽��ֱ�� of Cambridge. They also found that mindfulness may be no better than other practices aimed at improving mental health and wellbeing.

Mindfulness training in the community needs to be implemented with care. Community mindfulness courses should be just one option among others

Julieta Galante

World Economic Forum

Mindfulness meditation

̽��ֱ��text in this work is licensed under a Creative Commons Attribution 4.0 International License. Images, including our videos, are Copyright © ̽��ֱ�� of Cambridge and licensors/contributors as identified. All rights reserved. We make our image and video content available in a number of ways – as here, on our main website under its Terms and conditions, and on a range of channels including social media that permit your use and sharing of our content under their respective Terms.

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Autistic adults have a higher rate of physical health conditions

Anonymous — Thu, 10 Sep 2020 15:22:52 +0000

Earlier research has shown that autistic people on average die younger than others and that this may be, in part, due to chronic physical health conditions. Previous studies have also shown that autistic people are at higher risk of a variety of health conditions, but we don’t know what is driving these increased risks. Thus, better understanding of the physical health of autistic adults may help us improve both their quality and length of life.

1,156 autistic individuals and 1,212 non-autistic individuals took part in an anonymous, online survey developed by the team about their lifestyle choices and daily habits, personal and family medical history. ̽��ֱ��results indicate that autistic individuals are, on average, 1.5 to 4.3 times as likely to have a wide variety of health conditions, including low blood pressure, arrhythmias, asthma, and prediabetes.

This new study is also the first to examine the influence of smoking, alcohol use, and BMI. Surprisingly, the results show that these lifestyle factors (which increase the risk of chronic physical health problems in the general population) do not account for the heightened risk of heart, lung, and diabetic conditions seen among autistic adults.

̽��ֱ��study also explored the experiences of female respondents and of older adults, both of whom remain understudied groups. ̽��ֱ��results revealed that autistic females, even more so than autistic males, are more likely to report increased risks of physical health conditions. In addition, the types of conditions of risk depend on the person’s biological sex. For example, autistic females are 4.3 times more likely to have prediabetes than non-autistic females; however, autistic and non-autistic males are equally likely to have prediabetes. These results suggest that a “one size fits all” approach to the healthcare of autistic people may not be effective.

Elizabeth Weir, the PhD student who led the study, said: “This is a first step in better understanding why autistic individuals are so much more likely to have chronic physical health problems. While smoking, alcohol, and BMI may play a role, we now need to focus on what other biological (e.g. genetic, hormonal, etc), environmental, lifestyle (e.g. diet, exercise, sleep, etc) or healthcare-related factors are contributing to these health disparities.”

Professor Simon Baron-Cohen, Director of the Autism Research Centre at Cambridge, who was part of the team, said: “This new study highlights the physical health risks to autistic individuals, and has important implications for their healthcare. Understanding the reasons why these disparities exist will allow us to better support autistic individuals and improve the quality and length of their lives.”

Funding for this project was provided by the Autism Research Trust, the Rosetrees Trust, and the Cambridge and Peterborough NHS Foundation Trust.

Reference
Weir, E at al. Increased prevalence of non-communicable physical health conditions among autistic adults. Autism; 9 Sept 2020; DOI: 10.1177/1362361320953652

Autistic individuals are more likely to have chronic physical health conditions, particularly heart, lung, and diabetic conditions, according to a new study by researchers at the ̽��ֱ�� of Cambridge. ̽��ֱ��results are published in the journal Autism.

This is a first step in better understanding why autistic individuals are so much more likely to have chronic physical health problems

Elizabeth Weir

tomwieden

Doctor testing blood pressure

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Recruitment underway as Cambridgeshire NHS trusts join COVID-19 vaccine trial

Anonymous — Thu, 11 Jun 2020 07:49:43 +0000

̽��ֱ��COV002 trial, developed by the ̽��ֱ�� of Oxford, aims to assess how well people across a broad range of ages could be protected from COVID-19 using a new vaccine called ChAdOx1 nCoV-19. It will also provide valuable information on safety of the vaccine and its ability to generate good immune responses against the virus.

Cambridgeshire and Peterborough NHS Foundation Trust (CPFT), Cambridge ̽��ֱ�� Hospitals NHS Foundation Trust and Royal Papworth Hospital NHS Foundation Trust are recruiting healthy staff aged between 18-55 years old who have not been infected with coronavirus but have regular face-to-face contact with COVID-19 patients, to take part in the trial.

Eligible participants will be randomised to receive one dose of either the trial vaccine (ChAdOx1 nCoV-19) or a licensed meningitis vaccine (MenACWY) that will be used as a ‘control’ for comparison. Following vaccination, participants will be followed up over 12 months.

Dr Estée Török from the Department of Medicine at the ̽��ֱ�� of Cambridge and Principal Investigator at Cambridge ̽��ֱ�� Hospitals NHS Foundation Trust, said: “Developing an effective vaccine is key to controlling the COVID-19 pandemic. We are delighted to be working with CPFT and Royal Papworth on this UK national priority vaccine trial. We are looking for healthy volunteers at high risk of COVID-19 infection at CUH to participate in this study and are most grateful to them for doing so.”

Dr Ben Underwood, Deputy Medical Director and Principal Investigator (study lead) at CPFT said: “We are grateful to all our staff for their brilliant response to the coronavirus pandemic. Our research teams are playing a vital role in international efforts to secure a vaccine, which we hope will protect those most at risk, save more lives and minimise the disruption caused by the virus. Thank you to all volunteers who take part and make clinical trials possible.”

Dr Robert Rintoul, Director, Papworth Trials Unit Collaboration, and Reader in Thoracic Oncology at the Department of Oncology, ̽��ֱ�� of Cambridge, said: “We at Royal Papworth Hospital are proud to be supporting research into possible vaccines and treatments for COVID-19. I would like to thank our staff members who have chosen to participate in this important public health project.”

Adapted from a press release by Cambridge ̽��ֱ�� Health Partners.

Recruitment has begun at three leading Cambridgeshire NHS Trusts for volunteers to take part in the nationwide COVID-19 vaccine trial.

Developing an effective vaccine is key to controlling the COVID-19 pandemic

Estee Torok

geralt

Coronavirus

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Most young people with increased suicide risk only display ‘mild to moderate’ mental distress – study

fpjl2 — Wed, 20 May 2020 10:32:01 +0000

̽��ֱ��vast majority of young people who self-harm or experience suicidal thoughts appear to have only mild or moderate mental distress, instead of more obvious symptoms associated with a diagnosable disorder, according to a new study.

As such, measures to reduce suicide risk in young people should focus on the whole population, not just those who are most distressed, depressed or anxious, said Cambridge ̽��ֱ�� researchers during Mental Health Awareness week.

They argue that small increases in stress across the entire population due to the coronavirus lockdown could cause far more young people to be at risk of suicide than can be detected through evidence of psychiatric disorders.

“It appears that self-harm and suicidal thinking among young people dramatically increases well within the normal or non-clinical range of mental distress,” said Professor Peter Jones, senior author of the study from Cambridge’s Department of Psychiatry.

“These findings show that public policy strategies to reduce suicide should support better mental health for all young people, not only those who are most unwell,” said Jones, who is also a consultant psychiatrist at Cambridgeshire and Peterborough NHS Foundation Trust and director of the NIHR Applied Research Collaboration East of England.

“Even modest improvements in mental health and wellbeing across the entire population may prevent more suicides than targeting only those who are severely depressed or anxious.”

̽��ֱ��Cambridge researchers conducted the study with colleagues from ̽��ֱ�� College London. It was supported by the Wellcome Trust and the National Institute for Health Research, and is recently published in the journal BMJ Open.

Recent studies suggest a broad range of mental health problems – depression, anxiety, impulsive behaviour, low self-esteem, and so on – can be taken as a whole to measure levels of “common mental distress” (CMD).

Researchers analysed levels of CMD in two large groups of young people through a series of questionnaires.

They also separately collected self-reported data on suicidal thinking and non-suicidal self-injury: predictive markers for increased risk of suicide – the second most common cause of death among 10-24 year-olds worldwide.

Both groups consisted of young people aged 14-24 from London and Cambridgeshire. ̽��ֱ��first contained 2,403 participants. ̽��ֱ��study’s methods – and findings – were then reproduced with a separate group of 1,074 participants.

“Our findings are noteworthy for being replicated in the two independent samples,” said Jones.

CMD scores increase in three significant increments above the population average: mild mental distress, followed by moderate, and finally severe distress and beyond – which often manifests as a diagnosable mental health disorder.

Those with severe mental distress came out highest for risk of suicide. However, the majority of all participants experiencing suicidal thoughts or self-harming – 78% and 76% respectively in the first sample, 66% and 71% in the second – ranked as having either mild or moderate levels of mental distress.

“Our findings help explain why research focusing on high-risk subjects has yet to translate into useful clinical tools for predicting suicide risk,” said Jones. “Self-harm and suicidal thoughts merit a swift response even if they occur without further evidence of a psychiatric disorder.”

̽��ֱ��findings point to a seemingly contradictory situation, in which most of the young people who take their own life may, in fact, be from the considerably larger pool of those deemed as low- or no-risk for suicide.

“It is well known that for many physical conditions, such as diabetes and heart disease, small improvements in the risks of the overall population translate into more lives saved, rather than focusing only on those at extremely high risk,” said Jones.

“This is called the ‘prevention paradox’, and we believe our study is the first evidence that mental health could be viewed in the same way. We need both a public health and a clinical approach to suicide risk.”

“We are surrounded by technology designed to engage the attention of children and young people, and its effect on wellbeing should be seen by industry as a priority beyond profit.”

“At a government level, policies affecting the economy, employment, education and housing, to health, culture and sport must all take account of young people; supporting their wellbeing is an investment, not a cost. This is particularly important as the widespread effects of the Covid-19 pandemic unfold.”

Reference:
Polek E, Neufeld SAS, Wilkinson P, Goodyer I, St Clair M, Prabhu G, Dolan RJ, Bullmore ET, Fonagy P, Stochl J, Jones PB. How do the prevalence and relative risk of non-suicidal self-injury and suicidal thoughts vary across the population distribution of common mental distress (the p factor)? Observational analyses replicated in two independent UK cohorts of young people. BMJ Open 2020;10:e032494. doi: 10.1136/bmjopen-2019-032494

Around 70% of young people who report self-harming or suicidal thoughts are within the normal or non-clinical range of mental distress.

Even modest improvements in mental health and wellbeing across the entire population may prevent more suicides than targeting only those who are severely depressed or anxious

Peter Jones

Joe Penna

Young woman

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