Defective mitochondria – the ‘batteries’ that power the cells of our bodies – could in future be repaired using gene-editing techniques. Scientists at the ̽»¨Ö±²¥ of Cambridge have shown that it is possible to modify the mitochondrial genome in live mice, paving the way for new treatments for incurable mitochondrial disorders.
Whole genome sequencing from a single blood test picks up 31% more cases of rare genetic disorders than standard tests, shortening the ‘diagnostic odyssey’ that affected families experience, and providing huge opportunities for future research.
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people.
A contagious form of cancer that can spread between dogs during mating has highlighted the extent to which dogs accompanied human travellers throughout our seafaring history. But the tumours also provide surprising insights into how cancers evolve by ‘stealing’ DNA from their host.
DNA and genealogical study confirms identity of remains found in Leicester and uncovers new truths about his appearance and Plantagenet lineage.
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