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Repurposed cancer drug helps to calm inflammation in arteries.

A new risk calculator will better predict people at high risk of heart and circulatory diseases years before they strike, and is ready for use across the UK and Europe, according to research published in the journal European Heart Journal.

Professor Ziad Mallat and his team have been shortlisted for a £30 million grant from the British Heart Foundation. If successful, atherosclerosis – hardening of the arteries – could become a thing of the past.

It is almost impossible for an injured heart to fully mend itself. Within minutes of being deprived of oxygen – as happens during a heart attack when arteries to the heart are blocked – the heart’s muscle cells start to die. Sanjay Sinha wants to mend these hearts so that they work again. 

An international study of 220,000 people has challenged the idea that obese people who have an “apple shape” (fat deposits on the middle section of the body) are at higher risk of heart attacks and strokes than obese people with other types of fat distribution.