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A prescription drug to treat high blood pressure has shown promise against conditions such as Parkinson’s, Huntington’s and forms of dementia in studies carried out in mice and zebrafish at the ̽»¨Ö±²¥ of Cambridge.

Scientists have identified special types of brain cells that may allow us to simulate the decision-making processes of others, thereby reconstructing their state of mind and predicting their intentions. Dysfunction in these ‘simulation neurons’ may help explain difficulties with social interactions in conditions such as autism and social anxiety.

Low levels of oxygen in the womb – which can be caused by smoking or conditions such as pre-eclampsia – may cause problems with fertility later in life, a study carried out in rats suggests.

Offspring whose mothers had a complicated pregnancy may be at greater risk of heart disease in later life, according to a new study in sheep. ̽»¨Ö±²¥research, led by a team at the ̽»¨Ö±²¥ of Cambridge, suggests that our cards may be marked even before we are born.

‘Anhedonia’ (the loss of pleasure) is one of the key symptoms of depression. An important component of this symptom is an inability to feel excitement in anticipation of events; however the brain mechanisms underlying this phenomenon are poorly understood.

Our bodies contain two types of fat: white fat and brown fat. While white fat stores calories, brown fat burns energy and could help us lose weight. Now, scientists at the ̽»¨Ö±²¥ of Cambridge have found a way of making the white fat ‘browner’ and increasing the efficiency of brown fat.

Understanding Animal Research, an organisation promoting greater openness about animal research, has today released a list of the ten universities in the UK that conduct the highest number of animal procedures – those used in medical, veterinary and scientific research. These statistics are freely available on the universities’ websites as part of their ongoing commitment to transparency and openness.

Evidence has been building in recent years that our diet, our habits or traumatic experiences can have consequences for the health of our children – and even our grandchildren. ̽»¨Ö±²¥explanation that has gained most currency for how this occurs is so-called ‘epigenetic inheritance’ – patterns of chemical ‘marks’ on or around our DNA that are hypothesised to be passed down the generations. But new research from the ̽»¨Ö±²¥ of Cambridge suggests that this mechanism of non-genetic inheritance is likely to be very rare.

Researchers have developed a three-dimensional ‘organ on a chip’ which enables real-time continuous monitoring of cells, and could be used to develop new treatments for disease while reducing the number of animals used in research. 

A team of scientists at the ̽»¨Ö±²¥ of Cambridge has developed an artificial mouse embryo-like structure capable of forming the three major axes of the body. ̽»¨Ö±²¥technique, reported today in the journal Nature, could reduce the use of mammalian embryos in research.