Set up for life

25 November 2020

We’re used to the idea that as adults we have some control over our destiny: what we eat and drink and how much we exercise can affect our health. But the risks of heart disease and diabetes can be programmed much earlier – even before we are born.

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Confocal micrograph showing the superior saggital sinus in the mouse. Immune cells are shown in green lining this tube, and blood vessels in red

Why it takes guts to protect the brain against infection

04 November 2020

̽»¨Ö±²¥brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally in its protection: the gut.

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Fluorescent images showing gene expression in human embryos at early and late stage of pre-implantation development, where blue is each cell of the embryo, green is a cell membrane marker, magenta is a placental gene expression.

Placenta is initiated first, as cells of a fertilised egg divide and specialise

23 September 2020

̽»¨Ö±²¥first stages of placental development take place days before the embryo starts to form in human pregnancies. This newÌýfinding highlights the importance of healthy placental development in pregnancy, and could lead to future improvements in fertility treatments such asÌýIVF, and a better understanding of placental-related diseases in pregnancy.

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