From the way we learn, to how our memories are made and stored, the workings of our brains depend on connections forged between billions of neurons, yet much about how our nervous system develops remains a mystery.

There are two main benefits to sharing. As well as leading to other collaborations and more interesting research, it also means that other people can check what you鈥檝e done, which leads to more robust research.

Dr Stephen Eglen

Now, researchers at Cambridge, York, Newcastle and Imperial College London have developed a system allowing neurophysiologists to share raw data with each other, something they hope will generate new discoveries in the field. 探花直播results are published in the journal .

探花直播first type of data they collected and standardised are recordings of so called 鈥榬etinal waves鈥. During early development, retinal neurons generate signals that rapidly spread across from one cell to another, much like a Mexican wave in a football stadium.听 These patterns of activity are thought to help forge the neural connections from the eye to the brain.

To record retinal waves, scientists use multielectrode arrays (tiny electrical devices). In this research, the team took 366 recordings from 12 different studies published between 1993 and 2014, converted them all to HDF5 鈥 a standard open source format 鈥 and published them in a web-based 鈥榲irtual laboratory鈥 called CARMEN.

According to lead author Dr Stephen Eglen from the Cambridge Computational Biology Institute: 鈥淯nlike other fields such as genomics, there hasn鈥檛 been much public data sharing in neuroscience, which could be because the data are heterogeneous and hard to annotate, or because researchers are reluctant to share data with a competitor.鈥

But Eglen believes there is much to be gained by a more cooperative approach. 鈥淭here are two main benefits to sharing,鈥 he said. 鈥淎s well as leading to other collaborations and more interesting research, it also means that other people can check what you鈥檝e done, which leads to more robust research. And if the taxpayer funds research, then I think it鈥檚 important for those results to be publicly available.鈥

CARMEN was a pilot project funded by the EPSRC, and is now supported by the BBSRC.


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