abstract blood cells

Anatomy of a decision: mapping early development

06 July 2016

In the first genome-scale experiment of its kind, researchers have gained new insights into how a mouse embryo first begins to transform from a ball of unfocussed cells into a small, structured entity. Published in Nature, the single-cell genomics study was led by the European Bioinformatics Institute (EMBL-EBI) and the ̽»¨Ö±²¥ of Cambridge.

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Chromosomes (cropped)

Early-stage embryos with abnormalities may still develop into healthy babies

29 March 2016

Abnormal cells in the early embryo are not necessarily a sign that a baby will be born with a birth defect such as Down’s syndrome, suggests new research carried out in mice at the ̽»¨Ö±²¥ of Cambridge. In a study published today in the journal Nature Communications, scientists show that abnormal cells are eliminated and replaced by healthy cells, repairing – and in some cases completely fixing – the embryo.

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Embryo development: Some cells are more equal than others even at four-cell stage

24 March 2016

Genetic ‘signatures’ of early-stage embryos confirm that our development begins to take shape as early as the second day after conception, when we are a mere four cells in size, according to new research led by the ̽»¨Ö±²¥ of Cambridge and EMBL-EBI. Although they seem to be identical, the cells of the two day-old embryo are already beginning to display subtle differences.

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Ebola virus

Scientists release Ebola sequencing data to global research community online

03 June 2015

A team of scientists, part of the international effort to curb further spread of the Ebola virus in Sierra Leone, has released its first dataset of the virus’ genetic structure online. ̽»¨Ö±²¥dataset will allow the global scientific community to monitor the pathogen’s evolution in real-time and conduct research that can lead to more effective strategies against further outbreaks.

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'Skin cancer selfies' (cropped)

Cancer-associated DNA changes exist in a quarter of normal skin cells

21 May 2015

Normal skin contains an unexpectedly high number of cancer-associated mutations, according to a study published in Science. ̽»¨Ö±²¥findings illuminate the first steps cells take towards becoming a cancer and demonstrate the value of analysing normal tissue to learn more about the origins of the disease.

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