Articles about 'NIHR Cambridge Biomedical Research Centre'

Many cases of dementia may arise from non-inherited DNA ‘spelling mistakes’

15 October 2018

Only a small proportion of cases of dementia are thought to be inherited – the cause of the vast majority is unknown. Now, in a study published today in the journal Nature Communications, a team of scientists led by researchers at the ̽��ֱ�� of Cambridge believe they may have found an explanation: spontaneous errors in our DNA that arise as cells divide and replicate.

Baby’s sex affects mother’s metabolism and may influence risk of pregnancy-related complications

12 July 2018

̽��ֱ��sex of a baby controls the level of small molecules known as metabolites in the pregnant mother’s blood, which may explain why risks of some diseases in pregnancy vary depending whether the mother is carrying a boy or a girl, according to new research from the ̽��ֱ�� of Cambridge.

Advances in brain imaging settle debate over spread of key protein in Alzheimer’s

05 January 2018

Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads throughout the brain in Alzheimer’s disease – and hence that blocking its spread may prevent the disease from taking hold.

Running on autopilot: scientists find important new role for ‘daydreaming’ network

23 October 2017

A brain network previously associated with daydreaming has been found to play an important role in allowing us to perform tasks on autopilot. Scientists at the ̽��ֱ�� of Cambridge showed that far from being just ‘background activity’, the so-called ‘default mode network’ may be essential to helping us perform routine tasks.

Restless legs syndrome study identifies 13 new genetic risk variants

13 October 2017

A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition.

Type 2 diabetes successfully managed online

28 September 2017

People with type 2 diabetes could improve their health by using a new web-based self-management tool, according to new research.

New way of predicting kidney function could improve chemotherapy dosing for many cancer patients

07 July 2017

Scientists at the ̽��ֱ�� of Cambridge have developed a new statistical model which estimates kidney function in patients with cancer. This is the most accurate model for estimating kidney function yet developed and should help cancer specialists treat their patients more safely and improve the accuracy of chemotherapy dosing. ̽��ֱ��model is now available free online.

Cocaine addiction leads to build-up of iron in brain

21 February 2017

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the ̽��ֱ�� of Cambridge. ̽��ֱ��study, published today in Translational Psychiatry, raises hopes that there may be a biomarker – a biological measure of addiction – that could be used as a target for future treatments.

Crohn’s disease risk and prognosis determined by different genes, study finds

09 January 2017

Researchers have identified a series of genetic variants that affect the severity of Crohn’s disease, an inflammatory bowel disease – but surprisingly, none of these variants appear to be related to an individual’s risk of developing the condition in the first place.

Anti-inflammatory drugs could help treat symptoms of depression, study suggests

18 October 2016

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some cases of depression, concludes a review led by the ̽��ֱ�� of Cambridge, which further implicates our immune system in mental health disorders.

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