An experimental cystic fibrosis drug has been shown to prevent the disease’s damage to the liver, thanks to a world-first where scientists grew mini bile ducts in the lab.
A team of researchers led by the ̽»¨Ö±²¥ of Cambridge has described for the first time in humans how the epigenome – the suite of molecules attached to our DNA that switch our genes on and off – is comprehensively erased in early primordial germ cells prior to the generation of egg and sperm.
Scientists at the ̽»¨Ö±²¥ of Cambridge have successfully created ‘mini-lungs’ using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.
̽»¨Ö±²¥order in which genetic mutations are acquired determines how an individual cancer behaves, according to research from the ̽»¨Ö±²¥ of Cambridge, published today in the New England Journal of Medicine.
̽»¨Ö±²¥first comprehensive computer model to simulate the development of blood cells could help in the development of new treatments for leukaemia and lymphoma, say researchers at the ̽»¨Ö±²¥ of Cambridge and Microsoft Research.
DefiniGEN is one of the first commercial opportunities to arise from Cambridge’s expertise in stem cell research. Here, we look at some of the fundamental research that enables it to supply liver and pancreatic cells for drug screening.
Looking at stem cells through physicists’ eyes is challenging some of our basic assumptions about the body’s master cells.
Stem cells – the body’s master cells – demonstrate a bizarre property never before seen at a cellular level, according to a study published today from scientists at the ̽»¨Ö±²¥ of Cambridge.
A new technique for determining what causes stem cells to convert into other cell types could revolutionise our understanding of how genes function.
Cambridge researchers developing new therapies as part of a collaborative programme with industry.
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